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· · COA & SDS Disponível para todos os produtos · Envio no mesmo dia em itens em estoque MaxiPost - Moligand™, ≥98%(HPLC) , Voltage-gated potassium channel KCNQ3/KCNQ4 activator, CAS No.187523-35-9, Voltage-gated potassium channel KCNQ3/KCNQ4 activator
Disponível para encomenda
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC) Synonyms
(S)-II | FLINDOKALNER [INN] | HMS555I10 | (S)-3-(5-Chloro-2-methoxy-phenyl)-3-fluoro-6-trifluoromethyl-1,3-dihydro-indol-2-one | BDBM50426567 | (S)-(+)-BMS 204352 | Flindokalner [USAN:INN] | (+)-MAXIPOST | Flindokalner (USAN/INN) | J57O328W4W | BMS 204352
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Sinónimos
(S)-II | FLINDOKALNER [INN] | HMS555I10 | (S)-3-(5-Chloro-2-methoxy-phenyl)-3-fluoro-6-trifluoromethyl-1,3-dihydro-indol-2-one | BDBM50426567 | (S)-(+)-BMS 204352 | Flindokalner [USAN:INN] | (+)-MAXIPOST | Flindokalner (USAN/INN) | J57O328W4W | BMS 204352
Especificações e pureza
Moligand™, ≥98%(HPLC)
Mecanismos bioquímicos e fisiológicos
Potassium channel modulator. Acts as a positive modulator at neuronal Kv7 channels and calcium-activated K+channels (BKCa) in HEK293 cells. Displays negative modulatory activity at Kv7.1 channels (Ki= 3.7μM) and GABAAreceptors. Displays anxiolytic activit
Condições de armazenamento de armazenamento
Store at -20°C
Enviado em
Ice chest + Ice pads
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Tipo de ação
ACTIVATOR, OPENER
Mecanismo de ação
Voltage-gated potassium channel KCNQ3/KCNQ4 activator
Propriedades do produto Nomes e identificadores Pubchem Sid 528765600 Sorrisos canónicos COC1=C(C=C(C=C1)Cl)C2(C3=C(C=C(C=C3)C(F)(F)F)NC2=O)F IUPAC Name (3S)-3-(5-chloro-2-methoxyphenyl)-3-fluoro-6-(trifluoromethyl)-1H-indol-2-one InChIKey ULYONBAOIMCNEH-HNNXBMFYSA-N INCHI 1S/C16H10ClF4NO2/c1-24-13-5-3-9(17)7-11(13)15(18)10-4-2-8(16(19,20)21)6-12(10)22-14(15)23/h2-7H,1H3,(H,22,23)/t15-/m0/s1 SMILES isoméricas COC1=C(C=C(C=C1)Cl)[C@]2(C3=C(C=C(C=C3)C(F)(F)F)NC2=O)F RTECS NM3249000 Peso molecular 359.7 Reaxy-Rn 9149203 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9149203&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Classe Indoles and derivatives Subclass Indolines Intermediate Tree Nodes Not available Direct Parent Indolines Alternative Parents Phenoxy compounds Anisoles Methoxybenzenes Alkyl aryl ethers Chlorobenzenes Aryl chlorides Secondary carboxylic acid amides Lactams Azacyclic compounds Hydrocarbon derivatives Organochlorides Carbonyl compounds Organopnictogen compounds Organofluorides Organonitrogen compounds Alkyl fluorides Organic oxides Molecular Framework Aromatic heteropolycyclic compounds Substituents Dihydroindole - Phenoxy compound - Anisole - Phenol ether - Methoxybenzene - Alkyl aryl ether - Halobenzene - Chlorobenzene - Aryl chloride - Aryl halide - Monocyclic benzene moiety - Benzenoid - Lactam - Carboxamide group - Secondary carboxylic acid amide - Carboxylic acid derivative - Azacycle - Ether - Organic nitrogen compound - Organohalogen compound - Organochloride - Organofluoride - Organonitrogen compound - Organooxygen compound - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Alkyl halide - Alkyl fluoride - Aromatic heteropolycyclic compound Descrição This compound belongs to the class of organic compounds known as indolines. These are compounds containing an indole moiety, which consists of pyrrolidine ring fused to benzene to form 2,3-dihydroindole. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estrutura 3D Alvos associados (humanos) Alvos associados (não humanos) Mecanismos de ação Certificados（CoA,COO,BSE/TSE e Mapa de Análise) Propriedades químicas e físicas Solubilidade Solvent:DMSO, Max Conc. mg/mL: 35.97, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 35.97, Max Conc. mM: 100 Peso molecular 359.700 g/mol XLogP3 4.200 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 2 Exact Mass 359.034 Da Monoisotopic Mass 359.034 Da Topological Polar Surface Area 38.300 Ų Heavy Atom Count 24 Formal Charge 0 Complexity 503.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 1 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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Reconstitution Calculator Revisões Need help choosing the grade? Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →
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