MAZ51 - 10mM in DMSO , CAS No.163655-37-6

CAS: 163655-37-6 Cat. No.: M422009 Fórmula: C₂₁H₁₈N₂O Peso molecular: 314.38 Número CE: 634-088-2

GRADE & PURITY 10mM in DMSO

Synonyms

MAZ51|163655-37-6|3-[[4-(dimethylamino)naphthalen-1-yl]methylidene]-1H-indol-2-one|SCHEMBL3374614|MAZ-51;MAZ 51|VFCXONOPGCDDBQ-UHFFFAOYSA-N|BCP31595|Q27165368|3-(4-Dimethylaminonaphthalen-1-ylmethylene)-1,3-dihydroindol-2-one|3-[[4-(dimethylamino)-1-napht

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral

MAZ51 inhibits vascular endothelial cell growth factor-C (VEGF-C)-induced intracellular phosphorylation of Flt-4 (VEGFR-3) (IC|50|= 1 μM). MAZ51 is an inhibitor of Flt-4.

Specifications

Sinónimos

MAZ51 | 163655-37-6 | 3-[[4-(dimethylamino)naphthalen-1-yl]methylidene]-1H-indol-2-one | SCHEMBL3374614 | MAZ-51;MAZ 51 | VFCXONOPGCDDBQ-UHFFFAOYSA-N | BCP31595 | Q27165368 | 3-(4-Dimethylaminonaphthalen-1-ylmethylene)-1,3-dihydroindol-2-one | 3-[[4-(dimethylamino)-1-napht

Especificações e pureza

10mM in DMSO

Condições de armazenamento de armazenamento

Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Propriedades do produto

• pKa: pKa: 12.78 (Predicted), pKa: 4.42 (Predicted)

Nomes e identificadores

• Pubchem Sid: 528765418
• Sorrisos canónicos: CN(C)C1=CC=C(C2=CC=CC=C21)C=C3C4=CC=CC=C4NC3=O
• IUPAC Name: 3-[[4-(dimethylamino)naphthalen-1-yl]methylidene]-1H-indol-2-one
• InChIKey: VFCXONOPGCDDBQ-UHFFFAOYSA-N
• INCHI: 1S/C21H18N2O/c1-23(2)20-12-11-14(15-7-3-4-9-17(15)20)13-18-16-8-5-6-10-19(16)22-21(18)24/h3-13H,1-2H3,(H,22,24)
• SMILES isoméricas: CN(C)C1=CC=C(C2=CC=CC=C21)C=C3C4=CC=CC=C4NC3=O
• WGK Alemanha: 3
• Peso molecular: 314.38
• Reaxy-Rn: 27760008
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=27760008&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Naphthalenes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Naphthalenes
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Naphthalenes
• Alternative Parents: Indolines Dialkylarylamines Secondary carboxylic acid amides Lactams Amino acids and derivatives Azacyclic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Naphthalene - Indole or derivatives - Dihydroindole - Dialkylarylamine - Tertiary aliphatic/aromatic amine - Amino acid or derivatives - Carboxamide group - Lactam - Secondary carboxylic acid amide - Tertiary amine - Carboxylic acid derivative - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Amine - Organic oxygen compound - Carbonyl group - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
• Descrição: This compound belongs to the class of organic compounds known as naphthalenes. These are compounds containing a naphthalene moiety, which consists of two fused benzene rings.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriedades químicas e físicas

• Índice de refração: n20D1.73 (Predicted)
• Ponto de ebulição (°C): 553.92° C at 760 mmHg (Predicted)
• Ponto de fusão (°C): 222.83° C (Predicted)
• Peso molecular: 314.400 g/mol
• XLogP3: 4.300
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 314.142 Da
• Monoisotopic Mass: 314.142 Da
• Topological Polar Surface Area: 32.299 Ų
• Heavy Atom Count: 24
• Formal Charge: 0
• Complexity: 512.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 1
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 1