Meprednisone - 10mM in DMSO , Glucocorticoid receptor agonist, CAS No.1247-42-3, Glucocorticoid receptor agonist

CAS: 1247-42-3 Cat. No.: M408621 Fórmula: C₂₂H₂₈O₅ Peso molecular: 372.455 Número CE: 214-996-1

GRADE & PURITY 10mM in DMSO

Synonyms

NSC 527579, SCH 4358 | (16β)​-17,​21-​dihydroxy-​16-​methyl-​pregna-​1,​4-​diene-​3,​11,​20-​trione

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral

Information

Meprednisone Meprednisone (NSC 527579, SCH 4358) is a glucocorticoid and a methylated derivative of prednisone.
In vitro

In vivo

Cell Data

cell lines：PM1 cells

Concentrations：

Incubation Time：

Powder Purity:≥98%

Specifications

Sinónimos

NSC 527579, SCH 4358 | (16β)​-17,​21-​dihydroxy-​16-​methyl-​pregna-​1,​4-​diene-​3,​11,​20-​trione

Especificações e pureza

10mM in DMSO

Mecanismos bioquímicos e fisiológicos

Meprednisone (NSC 527579, SCH 4358) is a glucocorticoid and a methylated derivative of prednisone.

Condições de armazenamento de armazenamento

Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

AGONIST

Mecanismo de ação

Glucocorticoid receptor agonist

Propriedades do produto

• ALogP: 1.9

Nomes e identificadores

• SMILES isoméricas: C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@H]3C(=O)C[C@@]2([C@]1(C(=O)CO)O)C)C
• Peso molecular: 372.455
• Reaxy-Rn: 3481452
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3481452&ln=

Propriedades químicas e físicas

• Ponto de fusão (°C): 204-206°C

Referências

1. Jianbo Li, Ertai Ye, Jingwen Huang, Meng Xu, Jieke Zhang, Junrong Zhang, Huijie Cai, Jinjie Zhang.  (2024)  Cysteine-modified PEGylated nanoparticles for targeted delivery of methylprednisolone to pancreatitis.  EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS,      [PMID:38199584] [10.1016/j.ejpb.2024.114179]

Perguntas frequentes

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1247-42-3, the molecular formula is C22H28O5, and the molecular weight is 372.455 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.