MitoTEMPOL - Moligand™, ≥98% , CAS No.1101113-39-6

CAS: 1101113-39-6 Cat. No.: M275627 Fórmula: C₃₂H₄₂BrNO₂P Peso molecular: 583.57

GRADE & PURITY Moligand™, ≥98%

Synonyms

2,2,6,6-tetramethyl-4-[[5-(triphenylphosphonio)pentyl]oxy]-1-piperidinyloxy, monobromide

Storage

Protected from light,Store at -20°C,Argon charged,Desiccated

Shipped In

Ice chest + Ice pads

Visão geral

MitoTEMPOL is a a mitochondria-targeted nitroxide that reduces mitochondrial O2-to H2O2.

Specifications

Sinónimos

2,2,6,6-tetramethyl-4-[[5-(triphenylphosphonio)pentyl]oxy]-1-piperidinyloxy, monobromide

Especificações e pureza

Moligand™, ≥98%

Mecanismos bioquímicos e fisiológicos

Mitochondria-targeted antioxidant agent. SOD mimetic Tempol derivative. Protects complex I and II/III respiration. Restores MnSOD activity. Shows cardioprotective effects in vivo.

Condições de armazenamento de armazenamento

Protected from light,Store at -20°C,Argon charged,Desiccated

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Grau

Moligand™

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥98%

Nomes e identificadores

• Pubchem Sid: 528765639
• Sorrisos canónicos: CC1(CC(CC(N1[O])(C)C)OCCCCC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C.[Br-]
• InChIKey: NCMZESLTQCMFES-UHFFFAOYSA-M
• INCHI: 1S/C32H42NO2P.BrH/c1-31(2)25-27(26-32(3,4)33(31)34)35-23-15-8-16-24-36(28-17-9-5-10-18-28,29-19-11-6-12-20-29)30-21-13-7-14-22-30;/h5-7,9-14,17-22,27H,8,15-16,23-26H2,1-4H3;1H/q+1;/p-1
• Peso molecular: 583.57
• Reaxy-Rn: 31789565
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=31789565&ln=

Propriedades químicas e físicas

• Solubilidade: Soluble in water to 100 mM；DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 10 mg/ml
• Sensibilidade: air and light sensitive