ML 218 hydrochloride - ≥99%(HPLC) , CAS No.2319922-08-0

CAS: 2319922-08-0 Cat. No.: M288331 Fórmula: C₁₉H₂₆Cl₂N₂O.HCl Peso molecular: 405.79 PubChem CID: 90488946

GRADE & PURITY ≥99%(HPLC)

Synonyms

3,5-Dichloro-N-[[(1α,5α,6-exo,6α)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hex-6-yl]methyl]-benzamide hydrochloride

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

Sinónimos

3,5-Dichloro-N-[[(1α,5α,6-exo,6α)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hex-6-yl]methyl]-benzamide hydrochloride

Especificações e pureza

≥99%(HPLC)

Mecanismos bioquímicos e fisiológicos

Selective inhibitor of T-type calcium channels (IC50values are 270 and 310 nM for Cav3.3 and Cav3.2 respectively in a patch EP assay). Decreases burst activity in STN neurons; reduces cataleptic behaviour in anin vivorat model of Parkinson's disease. Disp

Condições de armazenamento de armazenamento

Store at 2-8°C

Enviado em

Wet ice

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

INHIBITOR

Pureza

≥99%(HPLC)

Nomes e identificadores

• Sorrisos canónicos: CC(C)(C)CCN1CC2C(C1)C2CNC(=O)C3=CC(=CC(=C3)Cl)Cl.Cl
• IUPAC Name: 3,5-dichloro-N-[[(1S,5R)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hexan-6-yl]methyl]benzamide;hydrochloride
• InChIKey: IDCVEUISZZKMKJ-ZXVFAPHLSA-N
• INCHI: 1S/C19H26Cl2N2O.ClH/c1-19(2,3)4-5-23-10-16-15(17(16)11-23)9-22-18(24)12-6-13(20)8-14(21)7-12;/h6-8,15-17H,4-5,9-11H2,1-3H3,(H,22,24);1H/t15?,16-,17+
• SMILES isoméricas: CC(C)(C)CCN1C[C@@H]2[C@H](C1)C2CNC(=O)C3=CC(=CC(=C3)Cl)Cl.Cl
• PubChem CID: 90488946
• Peso molecular: 405.79

Propriedades químicas e físicas

• Solubilidade: Solvent:DMSO, Max Conc. mg/mL: 36.93, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 36.93, Max Conc. mM: 100

Perguntas frequentes

What is the purity of this product, and how is it determined?

This product is supplied at ≥99% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at 2–8 °C. Refrigerated storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2319922-08-0, the molecular formula is C??H??Cl?N?O.HCl, and the molecular weight is 405.79 g/mol. InChIKey IDCVEUISZZKMKJ-ZXVFAPHLSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.