ML218 - Moligand™ , Channel blocker of Ca v3.1;Channel blocker of Ca v3.2;Channel blocker of Ca v3.3, CAS No.M611937, Channel blocker of Ca v3.1;Channel blocker of Ca v3.2;Channel blocker of Ca v3.3

CAS: M611937 Cat. No.: M611937 PubChem CID: 45115620

GRAU & PUREZA Moligand™

Synonyms

A)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hex-6-yl]methyl]-benzamide | A,6-exo,6 | HMS3749A17 | Q27087022 | 1346233-68-8 | cid_45115620 | GTPL7720 | VU0413807-1 | CHEBI:91745 | ML 218 | ML218 | ML-218 | MS-25927 | VU0413807-2 | VU0424199-1 | FT-0603380

Storage

Room temperature

Especificações

Sinónimos

A)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hex-6-yl]methyl]-benzamide | A,6-exo,6 | HMS3749A17 | Q27087022 | 1346233-68-8 | cid_45115620 | GTPL7720 | VU0413807-1 | CHEBI:91745 | ML 218 | ML218 | ML-218 | MS-25927 | VU0413807-2 | VU0424199-1 | FT-0603380

Especificações e pureza

Moligand™

Condições de armazenamento de armazenamento

Room temperature

Grau

Moligand™

Tipo de ação

CHANNEL BLOCKER

Mecanismo de ação

Channel blocker of Ca v3.1;Channel blocker of Ca v3.2;Channel blocker of Ca v3.3

Nomes e identificadores

Sorrisos canónicos

O=C(c1cc(Cl)cc(c1)Cl)NC[C@@H]1[C@@H]2[C@H]1CN(C2)CCC(C)(C)C

IUPAC Name

3,5-dichloro-N-[[(1R,5S)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hexan-6-yl]methyl]benzamide

InChIKey

GSJIGYLGKSBYBC-OSYLJGHBSA-N

INCHI

1S/C19H26Cl2N2O/c1-19(2,3)4-5-23-10-16-15(17(16)11-23)9-22-18(24)12-6-13(20)8-14(21)7-12/h6-8,15-17H,4-5,9-11H2,1-3H3,(H,22,24)/t15-,16-,17+

SMILES isoméricas

CC(C)(C)CCN1C[C@@H]2[C@H](C1)C2CNC(=O)C3=CC(=CC(=C3)Cl)Cl

PubChem CID

45115620

Alvos associados (humanos)

CACNA1H Tclin Voltage-dependent T-type calcium channel subunit alpha-1H (1 Activities)

Discover Target: CACNA1H

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CACNA1G Tclin Voltage-dependent T-type calcium channel subunit alpha-1G (1 Activities)

Discover Target: CACNA1G

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CACNA1I Tclin Voltage-dependent T-type calcium channel subunit alpha-1I (1 Activities)

Discover Target: CACNA1I

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Propriedades químicas e físicas

• Peso molecular: 369.300 g/mol
• XLogP3: 4.900
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 368.142 Da
• Monoisotopic Mass: 368.142 Da
• Topological Polar Surface Area: 32.299 Ų
• Heavy Atom Count: 24
• Formal Charge: 0
• Complexity: 443.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Perguntas frequentes

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at room temperature.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is M611937. InChIKey GSJIGYLGKSBYBC-OSYLJGHBSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.