10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 10 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Myricitrin Myricitrin (Myricitrine), a flavonoid compound isolated from the root bark of Myrica cerifera, which exerts antinociceptive effects.
In vitro
Myricitrin, a flavonoid compound isolated from the root bark of Myrica cerifera, which exerts antinociceptive effect. Myricitrin produces pronounced antinociception against chemical and mechanical models of pain in rodents via preventing the protein kinase C (PKC) alpha and PKC epsilon activation by phorbol myristate acetate (PMA). Another study proves that opening of voltage- and small-conductance calcium-gated K(+) channels and reduction of calcium influx leads to the antinociceptive of myricitrin. Myricitrin also decreases H2O2-induced apoptosis in vascular endothelial cells via inhibition of p53 gene expression, activation of caspase-3 and the MAPK signaling pathway, and alteration of the patterns of pro-apoptotic and anti-apoptotic gene expression.
In vivo
In mice, myricitrin (i.p. 10 mg/kg or 30 mg/kg) blocks apomorphine-induced stereotypy and climbing, and increases hindlimb retraction time (HRT).
Cell Data
cell lines：DU-145
Concentrations：
Incubation Time：
Powder Purity:≥99%
| SMILES isoméricas | C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC(=C(C(=C4)O)O)O)O)O)O |
|---|---|
| WGK Alemanha | 3 |
| Peso molecular | 464.38 |
| Reaxy-Rn | 25132980 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25132980&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Rotação específica [α] | -149 to -154 deg(C=0.5、MeOH) |
|---|---|
| Ponto de fusão (°C) | 197°C |
| 1. Ying Li, Haiming Hu, Huabing Yang, Aizhen Lin, Hui Xia, Xue Cheng, Mingwang Kong, Hongtao Liu. (2022) Vine Tea (Ampelopsis grossedentata) Extract Attenuates CCl4-Induced Liver Injury by Restoring Gut Microbiota Dysbiosis in Mice. MOLECULAR NUTRITION & FOOD RESEARCH, 66 (9): (2100892). [PMID:35188709] [10.1002/mnfr.202100892] |
| 2. Yilong Liu, Xianan Zhang, Liuhuan Zhan, Chang Xu, Linxiao Sun, Huamin Jiang, Chongde Sun, Xian Li. (2020) LC-Q-TOF-MS Characterization of Polyphenols from White Bayberry Fruit and Its Antidiabetic Effect in KK-Ay Mice. ACS Omega, [PMID:32715269] [10.1021/acsomega.0c02759] |
| 3. Yu-Mei Zhao, Lv-Huan Wang, Si-Fan Luo, Qi-Qin Wang, Ruin Moaddel, Ting-Ting Zhang, Zheng-Jin Jiang. (2018) Magnetic beads-based neuraminidase enzyme microreactor as a drug discovery tool for screening inhibitors from compound libraries and fishing ligands from natural products. JOURNAL OF CHROMATOGRAPHY A, [PMID:30005943] [10.1016/j.chroma.2018.07.031] |
| 4. Yang Huang, Ying Feng, Guangyun Tang, Minyi Li, Tingting Zhang, Marianne Fillet, Jacques Crommen, Zhengjin Jiang. (2017) Development and validation of a fast SFC method for the analysis of flavonoids in plant extracts. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, [PMID:28347593] [10.1016/j.jpba.2017.03.012] |
| 5. Chao-Yue Sun, Wan-Qing Li, Jing-Wen Lu, Ao-Yue Zhang, Qing-Xia Chu, Li Tang, Wei Gao, Jin-Jie Cai, Ying Lu, Dong Liu. (2025) Ampelopsis grossedentata protects against ethanol-induced acute duodenal injury by inhibiting TNF-triggered caspases-dependent apoptosis in mice. JOURNAL OF ETHNOPHARMACOLOGY, [PMID:40854417] [10.1016/j.jep.2025.120462] |
| 6. Hongting Deng, Yuanju He, Hui Cao, Lei Chen, Hui Teng. (2022) New insight into the effect of hydroxyl substituted flavonoids on the cytotoxicity of 2-amino-3-methylimidazo[4,5-f]quinoline. Food Frontiers, 4 (1): (289-296). [PMID:] [10.1002/fft2.194] |
| 7. Suyun Lin, Guowen Zhang, Yijing Liao, Junhui Pan, Deming Gong. (2015) Dietary Flavonoids as Xanthine Oxidase Inhibitors: Structure–Affinity and Structure–Activity Relationships. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:26285120] [10.1021/acs.jafc.5b03386] |
| 8. Tianze Xin, Yuqing Xu, Bixian Han, Zuoqing Li, Quansheng Liu, Hanxiang Li, Bingqiang Xu. (2026) Chemophenetic characterization of Pleuropterus multiflorus and Pleuropterus angulatus based on UPLC-MS/MS and molecular networking. BIOCHEMICAL SYSTEMATICS AND ECOLOGY, [PMID:] [10.1016/j.bse.2026.105238] |
| 9. Weiwei Wu, Yanming Tuo, Zhihui Wang, Na Chen, Yuxue Jiang, Chuanjiu Wu, Yongquan Xu, Wen Zeng, Weijiang Sun. (2026) Comprehensive analysis of taste variations and pleasantness components in white tea from different organs of Camellia sinensis cv. Fuding Dabaicha. FOOD CHEMISTRY, [PMID:41702009] [10.1016/j.foodchem.2026.148437] |
| 10. Yuchen Ma, Chang Liu, Yuanping Ye, Danyun Cheng, Yahui Guo, He Qian, Yuliang Cheng. (2026) Myricitrin enhances allocholic acid metabolism to restore gut barrier and alleviate ulcerative colitis in mice via the microbiota-metabolite-host axis. Food Bioscience, [PMID:] [10.1016/j.fbio.2026.108670] |
