NDSB-221 - ≥97% , CAS No.160788-56-7

CAS: 160788-56-7 Cat. No.: N276111 Fórmula: C₉H₁₉NO₃S Peso molecular: 221.32 Número CE: 687-439-7

GRAU & PUREZA ≥97%

Synonyms

NDSB 221 | 3-(1-methylpiperidinio)-1-propanesulfonate | J-009754 | SCHEMBL2396073 | non-detergent sulfobetaine 221 | DTXSID001213424 | 3-(1-Methylpiperidin-1-ium-1-yl)propane-1-sulfonate | HY-135463 | CHEBI:63318 | LCZC1460 | non detergent sulfobetaine 22

Storage

Room temperature,Argon charged

Shipped In

Normal

Visão geral

Product description
NDSB 221 is a nondetergent sulfobetaine that has been found to improve unfolding reversibility.
Product Application

NDSB 221 has been used in a study to identify a novel ligand binding site in phosphoserine phosphatase from Thermococcus onnurineus. It has also been used in a study to investigate its effects on acidic fibroblast growth factor (aFGF).
Non-detergent sulfobetaine is a compound used for non-denaturing protien purification. Increases the extraction yield of membrane, nuclear and cytoskeletal associated proteins. Zwitterionic over a wide pH range, easily removed by dialysis and no significant absorption in the near UV range. Specific applications include microsomal protein extraction, nuclear protein recovery, precipitation reduction in IEF, and membrane-bound protease purification. The typical usage concentration is 0.5 - 2.0 M.

Especificações

Sinónimos

NDSB 221 | 3-(1-methylpiperidinio)-1-propanesulfonate | J-009754 | SCHEMBL2396073 | non-detergent sulfobetaine 221 | DTXSID001213424 | 3-(1-Methylpiperidin-1-ium-1-yl)propane-1-sulfonate | HY-135463 | CHEBI:63318 | LCZC1460 | non detergent sulfobetaine 22

Especificações e pureza

≥97%

Mecanismos bioquímicos e fisiológicos

Zwitterionic non-detergent sulfobetaine. Used to extract, solubilise and crystallise proteins. Prevents protein aggregation and promotes renaturation of denatured proteins.

Condições de armazenamento de armazenamento

Room temperature,Argon charged

Enviado em

Normal

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥97%

Nomes e identificadores

Pubchem Sid

488196547

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488196547

Sorrisos canónicos

C[N+]1(CCCCC1)CCCS(=O)(=O)[O-]

IUPAC Name

3-(1-methylpiperidin-1-ium-1-yl)propane-1-sulfonate

InChIKey

DQNQWAVIDNVATL-UHFFFAOYSA-N

INCHI

1S/C9H19NO3S/c1-10(6-3-2-4-7-10)8-5-9-14(11,12)13/h2-9H2,1H3

SMILES isoméricas

C[N+]1(CCCCC1)CCCS(=O)(=O)[O-]

Peso molecular

221.32

Reaxy-Rn

30123612

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=30123612&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Piperidines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Piperidines
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Piperidines
• Alternative Parents: Tetraalkylammonium salts Sulfonyls Organosulfonic acids Alkanesulfonic acids Azacyclic compounds Organopnictogen compounds Organic salts Organic oxides Hydrocarbon derivatives Amines
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Piperidine - Quaternary ammonium salt - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Organosulfonic acid - Sulfonyl - Alkanesulfonic acid - Tetraalkylammonium salt - Azacycle - Organic nitrogen compound - Organosulfur compound - Organonitrogen compound - Organic salt - Hydrocarbon derivative - Amine - Organic oxide - Organopnictogen compound - Organic oxygen compound - Aliphatic heteromonocyclic compound
• Descrição: This compound belongs to the class of organic compounds known as piperidines. These are compounds containing a piperidine ring, which is a saturated aliphatic six-member ring with one nitrogen atom and five carbon atoms.
• External Descriptors: ammonium betaine

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriedades químicas e físicas

• Solubilidade: Soluble in water to 100 mM
• Sensibilidade: Moisture sensitive
• Peso molecular: 221.320 g/mol
• XLogP3: 0.300
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 221.109 Da
• Monoisotopic Mass: 221.109 Da
• Topological Polar Surface Area: 65.600 Ų
• Heavy Atom Count: 14
• Formal Charge: 0
• Complexity: 249.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1