Nedaplatina - ≥99% , CAS No.95734-82-0

CAS: 95734-82-0 Cat. No.: N129652 Fórmula: C₂H₈N₂O₃Pt Peso molecular: 303.17 Número CE: 111-811-5 PubChem CID: 6917890

GRADE & PURITY ≥99%

Synonyms

Aqupla | (Glicolato-O,O')diaminaplatina(II) | cis-Diamina(glicolato)platina(II)

Storage

Armazenar a -20°C

Shipped In

Arca de gelo + almofadas de gelo

Visão geral

A nedaplatina é um derivado da cisplatina e um agente de danos no ADN para unidades formadoras de colónias tumorais com IC50 de 94 μM
Um complexo de platina que tem uma potente atividade antineoplásica

Specifications

Sinónimos

Aqupla | (Glicolato-O,O')diaminaplatina(II) | cis-Diamina(glicolato)platina(II)

Especificações e pureza

≥99%

Mecanismos bioquímicos e fisiológicos

A nedaplatina é um complexo de platina que possui uma potente atividade antineoplásica. Derivado da cisplatina. Apresenta efeitos antineoplásicos e antitumorais in vitro.

Condições de armazenamento de armazenamento

Armazenar a -20°C

Enviado em

Arca de gelo + almofadas de gelo

Nota

Sempre que possível, deve preparar e utilizar as soluções no mesmo dia. No entanto, se precisar de preparar soluções de reserva com antecedência, recomendamos que guarde a solução como alíquotas em frascos hermeticamente fechados a -20°C. Em geral, estas podem ser utilizadas durante um mês. Antes de utilizar, e antes de abrir o frasco para injectáveis, recomendamos que deixe o seu produto equilibrar à temperatura ambiente durante pelo menos 1 hora. Precisa de mais conselhos sobre solubilidade, utilização e manuseamento? Para mais informações, visite a nossa página de perguntas frequentes (FAQ).

Pureza

≥99%

Nomes e identificadores

• Pubchem Sid: 504764342
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504764342
• Sorrisos canónicos: C(C(=O)O)O.N.N.[Pt]
• IUPAC Name: azane;2-hydroxyacetic acid;platinum
• InChIKey: ZAXCMPAWRCMABN-UHFFFAOYSA-N
• INCHI: 1S/C2H4O3.2H3N.Pt/c3-1-2(4)5;;;/h3H,1H2,(H,4,5);2*1H3
• SMILES isoméricas: C(C(=O)O)O.N.N.[Pt]
• PubChem CID: 6917890
• Termos de entrada MeSH: (glycolato-O,O')diammineplatinum II;254-S;CGDP-II;cis-diammine(glycolato)platinum II;nedaplatin;NSC 375101D;NSC-375101D
• Peso molecular: 303.17

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Hydroxy acids and derivatives
      • Subclass Alpha hydroxy acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Hydroxy acids and derivatives
• Subclass: Alpha hydroxy acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Alpha hydroxy acids and derivatives
• Alternative Parents: Organic transition metal salts Monocarboxylic acids and derivatives Carboxylic acids Primary alcohols Organic oxides Hydrocarbon derivatives Carbonyl compounds Amines
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alpha-hydroxy acid - Organic transition metal salt - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Primary alcohol - Organooxygen compound - Carbonyl group - Amine - Alcohol - Aliphatic acyclic compound
• Descrição: This compound belongs to the class of organic compounds known as alpha hydroxy acids and derivatives. These are organic compounds containing a carboxylic acid substituted with a hydroxyl group on the adjacent carbon.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriedades químicas e físicas

• Solubilidade: Soluble in water at 10 mg/mL.
• Sensibilidade: light sensitive
• Peso molecular: 305.200 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 305.034 Da
• Monoisotopic Mass: 305.034 Da
• Topological Polar Surface Area: 59.500 Ų
• Heavy Atom Count: 8
• Formal Charge: 0
• Complexity: 44.100
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 4

XLogP3

Referências

1. Sai-Nan Qin, Yi-Xue Zhang, Yi-Jie Cao, Ting Wan, Yi-Yang Zhou, Shan-Shan Su, Yu-Qiong Guo, Jian-Jun Sun, Kalle Salminen.  (2026)  A self-assembled electrochemical aptasensor for one-step rapid detection of cisplatin in blood via aptamer conformational change.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2026.116962]

Perguntas frequentes

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 95734-82-0, the molecular formula is C2H8N2O3Pt, and the molecular weight is 303.17 g/mol. InChIKey ZAXCMPAWRCMABN-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.