Neuropathiazol - ≥98%(HPLC) , CAS No.880090-88-0

CAS: 880090-88-0 Cat. No.: N287361 Fórmula: C₁₉H₁₈N₂O₂S Peso molecular: 338.42

GRADE & PURITY ≥98%(HPLC)

Synonyms

AKOS015919526 | BCPP000150 | Ethyl 4-(methyl(2-phenylthiazol-4-yl)amino)benzoate;Neuropathiazol | SCHEMBL8238620 | BCP02467 | A14058 | DTXSID80470323 | Ethyl 4-(methyl(2-phenylthiazol-4-yl)amino)benzoate | FT-0727742 | HB3105 | Ethyl 4-[methyl-(2-phenyl-1

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

Product description：

Neuropathiazol, a neuronal differentiation inducer, selectively induces neuronal differentiation of multipotent hippocampal neural progenitor cells.

Specifications

Sinónimos

AKOS015919526 | BCPP000150 | Ethyl 4-(methyl(2-phenylthiazol-4-yl)amino)benzoate;Neuropathiazol | SCHEMBL8238620 | BCP02467 | A14058 | DTXSID80470323 | Ethyl 4-(methyl(2-phenylthiazol-4-yl)amino)benzoate | FT-0727742 | HB3105 | Ethyl 4-[methyl-(2-phenyl-1

Especificações e pureza

≥98%(HPLC)

Mecanismos bioquímicos e fisiológicos

Selective inducer of neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs). Selectively suppresses astrocyte differentiation when induced by LIF, BMP2 and FBS compared to retinoic acid. Enhances maturation of NPC derived neurons.

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Pureza

≥98%(HPLC)

Nomes e identificadores

Pubchem Sid

488197653

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488197653

Sorrisos canónicos

CCOC(=O)C1=CC=C(C=C1)N(C)C2=CSC(=N2)C3=CC=CC=C3

IUPAC Name

ethyl 4-[methyl-(2-phenyl-1,3-thiazol-4-yl)amino]benzoate

InChIKey

MGKYEWWFHSESJN-UHFFFAOYSA-N

INCHI

1S/C19H18N2O2S/c1-3-23-19(22)15-9-11-16(12-10-15)21(2)17-13-24-18(20-17)14-7-5-4-6-8-14/h4-13H,3H2,1-2H3

SMILES isoméricas

CCOC(=O)C1=CC=C(C=C1)N(C)C2=CSC(=N2)C3=CC=CC=C3

Peso molecular

338.42

Reaxy-Rn

10453133

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=10453133&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Classe Organonitrogen compounds
      • Subclass Amines
        • Level5 Tertiary amines
          • Level6 Tertiary alkylarylamines
            • Level7 Alkyldiarylamines

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Classe: Organonitrogen compounds
• Subclass: Amines
• Intermediate Tree Nodes: Tertiary amines - Tertiary alkylarylamines
• Direct Parent: Alkyldiarylamines
• Alternative Parents: Benzoic acid esters Benzoyl derivatives Aniline and substituted anilines 2,4-disubstituted thiazoles Imidolactams Aminothiazoles Heteroaromatic compounds Carboxylic acid esters Azacyclic compounds Organooxygen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Alkyldiarylamine - Benzoate ester - Benzoic acid or derivatives - Benzoyl - Aniline or substituted anilines - 2,4-disubstituted 1,3-thiazole - Monocyclic benzene moiety - 1,3-thiazolamine - Benzenoid - Imidolactam - Thiazole - Heteroaromatic compound - Azole - Carboxylic acid ester - Carboxylic acid derivative - Azacycle - Organoheterocyclic compound - Organooxygen compound - Organic oxide - Organic oxygen compound - Hydrocarbon derivative - Aromatic heteromonocyclic compound
• Descrição: This compound belongs to the class of organic compounds known as alkyldiarylamines. These are tertiary alkylarylamines having two aryl and one alkyl groups attached to the amino group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Alvos associados (não humanos)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de ação

Propriedades químicas e físicas

• Solubilidade: Solvent:DMSO, Max Conc. mg/mL: 33.84, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 6.77, Max Conc. mM: 20
• Peso molecular: 338.400 g/mol
• XLogP3: 4.800
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 338.109 Da
• Monoisotopic Mass: 338.109 Da
• Topological Polar Surface Area: 70.700 Ų
• Heavy Atom Count: 24
• Formal Charge: 0
• Complexity: 406.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1