NHS-PEG-NHS - MW 6000 Da

Cat. No.: N164064

GRADE & PURITY MW 6000 Da

Synonyms

Bis-succinimidyl PEG Ester

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Visão geral

N-hydroxylsuccinimide (NHS) functionalized polyethylene glycol (PEG-NHS) is an amino (-NH₂) reactive PEG derivative that can be used to modify protein, peptide or any other surfaces with their available amino groups. NHS esters react with primary amine groups at pH 7~8.5 to form stable amide bonds.Compared to other PEG NHS ester derivatives, our succinimidyl carbonate (SC) functionalized mPEG-NHS offers superior reactivity and higher stability in aqueous solution. NHS esters react with deprotonated primary amines, therefore, the reaction requires neutral to basic pH values to proceed. Primary amines react with NHS esters by nucleophilic attack and NHS is released as a byproduct. Hydrolysis of the NHS-ester competes with the reaction in aqueous solution and increases with increasing pH.

Specifications

Sinónimos

Bis-succinimidyl PEG Ester

Especificações e pureza

MW 6000 Da

Mecanismos bioquímicos e fisiológicos

Generally, a 10 to 50-fold molar excess of NHS PEG over the amount of amine-containing material results in sufficient conjugation.

Materials Required:

• Conjugation buffer: Sodium bicarbonate 100 mM buffer, pH 8.5 or other amine-f

Condições de armazenamento de armazenamento

Store at -20°C,Argon charged

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Propriedades químicas e físicas

• Solubilidade: Soluble in regular aqeous solution as well as most organic solvents
• Sensibilidade: Moisture sensitive