Nimesulide - Moligand™, 10mM in DMSO , Inhibitor of B⁰AT1;Inhibitor of COX-1;Inhibitor of COX-2, CAS No.51803-78-2, Inhibitor of B⁰AT1;Inhibitor of COX-1;Inhibitor of COX-2

CAS: 51803-78-2 Cat. No.: N407977 Fórmula: C13H12N2O5S Peso molecular: 308.31 Número CE: 257-431-4
Disponível para encomenda
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
Synonyms
N-​(4-​nitro-​2-​phenoxyphenyl)​-methanesulfonamide
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Alemanha (EU)
USA*
Price
Qty
1ml
N407977-1ml
—
1 Em stock

92,76€

134,41€
Gravar 41,65 € (30.99%)
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 6 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Visão geral

Information

Nimesulide is a relativelyCOX-2selective inhibitor withIC50of 26 μM.
In vitro


In vivo


Cell Data

cell lines:HepG2 cells

Concentrations:

Incubation Time:

Powder Purity:≥99%

Specifications

Sinónimos
N-​(4-​nitro-​2-​phenoxyphenyl)​-methanesulfonamide
Especificações e pureza
Moligand™, 10mM in DMSO
Mecanismos bioquímicos e fisiológicos
Nimesulide is a relatively COX-2 selective inhibitor with IC50 of 26 μM.
Condições de armazenamento de armazenamento
Store at -80°C
Enviado em
Dry ice packs + Cold packs
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Grau
Moligand™
Tipo de ação
INHIBITOR
Mecanismo de ação
Inhibitor of B⁰AT1;Inhibitor of COX-1;Inhibitor of COX-2
Nomes e identificadores
SMILES isoméricas
CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2=CC=CC=C2
WGK Alemanha
3
RTECS
PB0970000
Peso molecular
308.31
Reaxy-Rn
2421175
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2421175&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Alvos associados (humanos)
SLC6A19 Tchem Sodium-dependent neutral amino acid transporter B(0)AT1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTGS1 Tclin Prostaglandin G/H synthase 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTGS2 Tclin Prostaglandin G/H synthase 2 (8 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificados(CoA,COO,BSE/TSE e Mapa de Análise)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propriedades químicas e físicas
SolubilidadeSolubility (25°C) In vitro DMSO: 66 mg/mL (198.11 mM); Ethanol: -1 mg/mL  
Ponto de fusão (°C)150 °C
FAQs e artigos
Citations of This Product
Calculadoras de soluções
Revisões

Avaliações dos Clientes

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