NSC689857 - ≥99% , CAS No.241127-79-7

Name: NSC689857 - ≥99% , CAS No.241127-79-7
Brand: Aladdin Scientific
SKU: N650022
Availability: InStock

CAS: 241127-79-7 Cat. No.: N650022 Molecular Weight: 407.50 PubChem CID: 391131

COA

Skip to the end of the images gallery

NSC689857 - ≥99% CAS No(241127-79-7) by Aladdin Scientific

Skip to the beginning of the images gallery

AVAILABLE TO ORDER

GRADE & PURITY ≥99%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview Specifications Names and Identifiers Documentation Advanced Data Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews

🧪

Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

NSC689857 is a potent EGFR and SCF SKP2 inhibitor with an IC 50 value of 36 μM for Skp2-Cks1. NSC689857 can inhibit p27 ubiquitylation (IC 50 =30 μM). NSC689857 has varied activity across cancer types, with more activity against leukemia cell lines than others

Form:Solid

IC50& Target:IC 50 : 36 μM (Skp2-Cks1), 30 μM (p27 ubiquitylation)

Specifications

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Purity

≥99%

Names and Identifiers

Isomeric SMILES	C1C2CC3CC1CC(C2)(C3)COC(=O)C4=CC=C(C=C4)NCC5=C(C=CC(=C5)O)O
PubChem CID	391131
Molecular Weight	407.50

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)

GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)

Discover Target: GLP1R

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A498 (42825 Activities)

Solubility	DMSO : 100 mg/mL (245.40 mM; Need ultrasonic)
Molecular Weight	407.500 g/mol
XLogP3	5.400
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	7
Exact Mass	407.21 Da
Monoisotopic Mass	407.21 Da
Topological Polar Surface Area	78.800 Å²
Heavy Atom Count	30
Formal Charge	0
Complexity	573.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1