Oleuropein - Moligand™, ≥98% , CAS No.32619-42-4

CAS: 32619-42-4 Cat. No.: O140217 Fórmula: C₂₅H₃₂O₁₃ Peso molecular: 540.51 Número CE: 251-129-6

GRADE & PURITY Moligand™, ≥98%

Synonyms

methyl (2S,3E,4S)-4-{2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl}-3-ethylidene-2-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,4-dihydro-2H-pyran-5-carboxylate | CCG-269961 | CHEBI:7747 | methyl (4S,5E,6S)-4-[2-[2-(3,4-dihydroxyph

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Visão geral

The primary phenolic compound found in olives and olive oil. Oleuropein hydrolyzes to form hydroxytyrosol and tyrosol, with hydroxytyrosol considered the main component associated with olive′s health benefits. Olive oil phenols demonstrate antioxidant, anti-thrombotic, anti-inflammatory and anti-atherogenic characteristics.
An antioxidant and immunomodulator in vitro that is a tyrosol ester derivative of elenolic acid and phenolic glycoside found naturally olive oil.

Specifications

Sinónimos

methyl (2S,3E,4S)-4-{2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl}-3-ethylidene-2-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,4-dihydro-2H-pyran-5-carboxylate | CCG-269961 | CHEBI:7747 | methyl (4S,5E,6S)-4-[2-[2-(3,4-dihydroxyph

Especificações e pureza

Moligand™, ≥98%

Mecanismos bioquímicos e fisiológicos

Oleuropein has been shown to augment the secretion of noradrenaline and adrenaline in rat.

Condições de armazenamento de armazenamento

Store at 2-8°C,Argon charged

Enviado em

Wet ice

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Grau

Moligand™

Pureza

≥98%

Nomes e identificadores

• Pubchem Sid: 508813748
• Sorrisos canónicos: CC=C1C(C(=COC1OC2C(C(C(C(O2)CO)O)O)O)C(=O)OC)CC(=O)OCCC3=CC(=C(C=C3)O)O
• IUPAC Name: methyl (4S,5E,6S)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-ethylidene-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4H-pyran-3-carboxylate
• InChIKey: RFWGABANNQMHMZ-ZCHJGGQASA-N
• INCHI: 1S/C25H32O13/c1-3-13-14(9-19(29)35-7-6-12-4-5-16(27)17(28)8-12)15(23(33)34-2)11-36-24(13)38-25-22(32)21(31)20(30)18(10-26)37-25/h3-5,8,11,14,18,20-22,24-28,30-32H,6-7,9-10H2,1-2H3/b13-3+/t14-,18+,20+,21-,22+,24-,25-/m0/s1
• SMILES isoméricas: C/C=C/1\[C@@H](C(=CO[C@H]1O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)C(=O)OC)CC(=O)OCCC3=CC(=C(C=C3)O)O
• WGK Alemanha: 3
• Peso molecular: 540.51
• Reaxy-Rn: 26520590
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=26520590&ln=

Alvos associados (humanos)

TAS2R8 Tchem Taste receptor type 2 member 8 (0 Activities)

Discover Target: TAS2R8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)

Discover Target: ALOX5

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HL-60 (67320 Activities)

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K562 (73714 Activities)

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MCF7 (126967 Activities)

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SK-BR-3 (5175 Activities)

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HCT-116 (91556 Activities)

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HeLa (62764 Activities)

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PBMC (10003 Activities)

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Alvos associados (não humanos)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

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Mus musculus (284745 Activities)

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RAW264.7 (28094 Activities)

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Verticillium dahliae (119 Activities)

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B16-F1 (104 Activities)

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Mecanismos de ação

Propriedades químicas e físicas

• Solubilidade: Soluble in water, acetone, ethanol, pyridine, glacial acetic acid , 5% aq NaOH, dioxane, butano, ethyl acetate, butyl acetate, DMF (50 mg/ml), and methanol. Insoluble in ether, chloroform, petr ether, benzene, and carbon tetrachloride.
• Sensibilidade: Hygroscopic
• Rotação específica [α]: -165° (C=0.5,EtOH)
• Ponto de fusão (°C): 89 °C
• Peso molecular: 540.500 g/mol
• XLogP3: -0.400
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 13
• Rotatable Bond Count: 11
• Exact Mass: 540.184 Da
• Monoisotopic Mass: 540.184 Da
• Topological Polar Surface Area: 202.000 Ų
• Heavy Atom Count: 38
• Formal Charge: 0
• Complexity: 873.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 7
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 1
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 1