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· · COA & SDS Disponível para todos os produtos · Envio no mesmo dia em itens em estoque PD 146176 - Moligand™, ≥98%(HPLC) , Inhibitor of 15-LOX-1, CAS No.4079-26-9, Inhibitor of 15-LOX-1
Disponível para encomenda
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC) Synonyms
6,11-Dihydro[1]benzothiopyrano[4,3-b]indole
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Visão geral PD 146176 has been used to study its influence on ex vivo leukotriene B4 (LTB4) and lipoxin A4 (LXA4) secretion in adipose tissue.
Specifications Sinónimos
6,11-Dihydro[1]benzothiopyrano[4,3-b]indole
Especificações e pureza
Moligand™, ≥98%(HPLC)
Mecanismos bioquímicos e fisiológicos
PD 146176 blocks neuroprotectin D1 (NPD1) and eicosanoid synthesis by inhibiting the 5-lipoxygenase-1 (15-LOX-1) enzyme.
15-Lipoxygenase inhibitor
Condições de armazenamento de armazenamento
Store at -20°C
Enviado em
Ice chest + Ice pads
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Mecanismo de ação
Inhibitor of 15-LOX-1
Nomes e identificadores Pubchem Sid 504758372 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504758372 Sorrisos canónicos C1C2=C(C3=CC=CC=C3S1)NC4=CC=CC=C24 IUPAC Name 6,11-dihydrothiochromeno[4,3-b]indole InChIKey ZGOOPZVQMLHPFM-UHFFFAOYSA-N INCHI 1S/C15H11NS/c1-3-7-13-10(5-1)12-9-17-14-8-4-2-6-11(14)15(12)16-13/h1-8,16H,9H2 SMILES isoméricas C1C2=C(C3=CC=CC=C3S1)NC4=CC=CC=C24 CAS alternativo 4079-26-9 PubChem CID 297589 Número NSC 168807 Termos de entrada MeSH 6,11-dihydro-5-thia-11-aza-benzo(a)-fluorene;PD 146176;PD-146176 Peso molecular 237.32
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Classe Indoles and derivatives Subclass Indoles Intermediate Tree Nodes Not available Direct Parent 3-alkylindoles Alternative Parents 1-benzothiopyrans Alkylarylthioethers Benzenoids Pyrroles Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents 3-alkylindole - 1-benzothiopyran - Benzothiopyran - Aryl thioether - Alkylarylthioether - Benzenoid - Heteroaromatic compound - Pyrrole - Azacycle - Thioether - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Aromatic heteropolycyclic compound Descrição This compound belongs to the class of organic compounds known as 3-alkylindoles. These are compounds containing an indole moiety that carries an alkyl chain at the 3-position. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estrutura 3D Alvos associados (humanos) Alvos associados (não humanos) Mecanismos de ação Certificados（CoA,COO,BSE/TSE e Mapa de Análise) Propriedades químicas e físicas Solubilidade Solvent:DMSO, Max Conc. mg/mL: 23.73, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 11.87, Max Conc. mM: 50 Peso molecular 237.320 g/mol XLogP3 3.800 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 1 Rotatable Bond Count 0 Exact Mass 237.061 Da Monoisotopic Mass 237.061 Da Topological Polar Surface Area 41.100 Ų Heavy Atom Count 17 Formal Charge 0 Complexity 293.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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