PD173952 - ≥99% , CAS No.305820-75-1

CAS: 305820-75-1 Cat. No.: P1421465 Molecular Weight: 482.36 PubChem CID: 5328733

GRADE & PURITY ≥99%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

PD173952 is a tyrosine kinases inhibitor with IC 50 s of 0.3, 1.7 and 6.6 nM against Lyn , Abl and Csk , respectively. PD173952 is also a potent Myt1 kinase inhibitor with a K i of 8.1 nM. PD173952 induces apoptosis.

Specifications

Specifications & Purity

≥99%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Purity

≥99%

Names and Identifiers

• Canonical Smiles: CN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=CC=C3Cl)Cl)NC4=CC=C(C=C4)N5CCOCC5
• IUPAC Name: 6-(2,6-dichlorophenyl)-8-methyl-2-(4-morpholin-4-ylanilino)pyrido[2,3-d]pyrimidin-7-one
• InChIKey: XZEJMVDCQZRHLN-UHFFFAOYSA-N
• INCHI: 1S/C24H21Cl2N5O2/c1-30-22-15(13-18(23(30)32)21-19(25)3-2-4-20(21)26)14-27-24(29-22)28-16-5-7-17(8-6-16)31-9-11-33-12-10-31/h2-8,13-14H,9-12H2,1H3,(H,27,28,29)
• Isomeric SMILES: CN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=CC=C3Cl)Cl)NC4=CC=C(C=C4)N5CCOCC5
• PubChem CID: 5328733
• Molecular Weight: 482.36

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Oxazinanes
      • Subclass Morpholines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Oxazinanes
• Subclass: Morpholines
• Intermediate Tree Nodes: Not available
• Direct Parent: Phenylmorpholines
• Alternative Parents: Phenylpyridines Pyrido[2,3-d]pyrimidines Aniline and substituted anilines Dialkylarylamines Dichlorobenzenes Pyridinones Aminopyrimidines and derivatives Aryl chlorides Heteroaromatic compounds Lactams Oxacyclic compounds Azacyclic compounds Dialkyl ethers Organochlorides Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Phenylmorpholine - 3-phenylpyridine - Pyrido[2,3-d]pyrimidine - Pyridopyrimidine - 1,3-dichlorobenzene - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Aniline or substituted anilines - Chlorobenzene - Halobenzene - Pyridinone - Aminopyrimidine - Aryl chloride - Pyrimidine - Benzenoid - Aryl halide - Pyridine - Monocyclic benzene moiety - Heteroaromatic compound - Tertiary amine - Lactam - Ether - Dialkyl ether - Oxacycle - Azacycle - Organochloride - Organohalogen compound - Organic nitrogen compound - Amine - Hydrocarbon derivative - Organic oxygen compound - Organic oxide - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as phenylmorpholines. These are aromatic compounds containing a morpholine ring and a benzene ring linked to each other through a CC or a CN bond.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y