Phthaldialdehyde Reagent - 0.8mg/mL solution (pH 10) , CAS No.643-79-8

CAS: 643-79-8 Cat. No.: P128626 Fórmula: C₈H₆O₂ Peso molecular: 134.13 Beilstein Registry Number: 878317 Número CE: 211-402-2

GRADE & PURITY 0.8mg/mL solution (pH 10)

Synonyms

1,2-Benzenedicarboxaldehyde | o-Phthaldialdehyde | Phthaldialdehyde | Benzene-1,2-dicarboxaldehyde | Phthalic dialdehyde | ortho-Phthalaldehyde | Phthalic dicarboxaldehyde | Phthalyldicarboxaldehyde | OPA | Phthalic aldehyde

Storage

Argon charged,Room temperature

Shipped In

Normal

Visão geral

Fluoraldehyde OPA Reagent is a ready-to-use solution of o-phthalaldehyde, a fluorescent derivatization reagent for peptide or amino acid detection and quantitation in HPLC. Fluoraldehyde Reagent Solution contains OPA (o-phthalaldehyde), which reacts with primary amines of amino acids, peptide and proteins to enable fluorescent detection and quantitation. The reagent that can be used as a protein or peptide assay reagent or as a pre- or post-column detection reagent for amino acid analysis (HPLC). Reaction of OPA with proteins and peptides yields linear results over a wide range of concentrations. The Fluoraldehyde Reagent Solution is supplied ready to use and enables fast quantitation of proteins or peptides in solution. Highlights: For pre- or post-column amino acid derivatization for fluorescent detection and quantitation Reacts with all primary amine-containing analytes to yield fluorescent isoindole derivatives Provides an accurate measure of both composition and absolute protein-peptide content Ideal for work with recombinant proteins and synthetic peptides Can be used for fluorescent protein or peptide assay Pre-column derivatization mixtures can be injected into LC without any processing
Precolumn derivatization reagent for primary amines and amino acids. The fluorescent derivative can be detected by reverse-phase HPLC. The reaction requires OPA, primary amine and a sulfhydryl. In the presence of excess sulfhydryl, amines can be quantitated. In the presence of excess amine, sulfhydryls can be quantitated.

Specifications

Sinónimos

1,2-Benzenedicarboxaldehyde | o-Phthaldialdehyde | Phthaldialdehyde | Benzene-1,2-dicarboxaldehyde | Phthalic dialdehyde | ortho-Phthalaldehyde | Phthalic dicarboxaldehyde | Phthalyldicarboxaldehyde | OPA | Phthalic aldehyde

Especificações e pureza

0.8mg/mL solution (pH 10)

Condições de armazenamento de armazenamento

Argon charged,Room temperature

Enviado em

Normal

Nomes e identificadores

• Pubchem Sid: 508816718
• Sorrisos canónicos: C1=CC=C(C(=C1)C=O)C=O
• IUPAC Name: phthalaldehyde
• InChIKey: ZWLUXSQADUDCSB-UHFFFAOYSA-N
• INCHI: 1S/C8H6O2/c9-5-7-3-1-2-4-8(7)6-10/h1-6H
• SMILES isoméricas: C1=CC=C(C(=C1)C=O)C=O
• WGK Alemanha: 3
• RTECS: TH6950000
• Número UN: 2923
• Grupo de embalagem: II
• Peso molecular: 134.13
• Beilstein: 878317
• Reaxy-Rn: 878317
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=878317&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Benzoyl derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Benzoyl derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Benzoyl derivatives
• Alternative Parents: Benzaldehydes Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Benzoyl - Benzaldehyde - Aryl-aldehyde - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Aldehyde - Aromatic homomonocyclic compound
• Descrição: This compound belongs to the class of organic compounds known as benzoyl derivatives. These are organic compounds containing an acyl moiety of benzoic acid with the formula (C6H5CO-).
• External Descriptors: benzaldehydes - dialdehyde

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Alvos associados (humanos)

VDR Tclin Vitamin D receptor (26531 Activities)

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THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)

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POLK Tbio DNA polymerase kappa (8653 Activities)

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EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

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LMNA Tbio Prelamin-A/C (36751 Activities)

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BLM Tchem Bloom syndrome protein (4248 Activities)

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GMNN Tbio Geminin (128009 Activities)

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PMP22 Tbio Peripheral myelin protein 22 (699 Activities)

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KMT2A Tchem Histone-lysine N-methyltransferase MLL (17327 Activities)

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USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)

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MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)

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Alvos associados (não humanos)

Mycobacteroides chelonae (540 Activities)

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Meloidogyne incognita (862 Activities)

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Mus musculus (284745 Activities)

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GCN5 Histone acetyltransferase GCN5 (89 Activities)

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ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)

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Mecanismos de ação

Propriedades químicas e físicas

• Sensibilidade: Air sensitive
• Ponto de inflamação (°F): 269.6 °F
• Ponto de inflamação (°C): >110℃
• Ponto de ebulição (°C): 84°C/0.8mmHg
• Ponto de fusão (°C): 56-57°C
• Peso molecular: 134.130 g/mol
• XLogP3: 1.200
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 134.037 Da
• Monoisotopic Mass: 134.037 Da
• Topological Polar Surface Area: 34.100 Ų
• Heavy Atom Count: 10
• Formal Charge: 0
• Complexity: 115.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1