Picloxydine - ≥98% , CAS No.5636-92-0

CAS: 5636-92-0 Cat. No.: P649325 Fórmula: C₂₀H₂₄Cl₂N₁₀ Peso molecular: 475.38 Número CE: 227-084-3 PubChem CID: 5748610

GRAU & PUREZA ≥98%

Synonyms

PICLOXYDINE [WHO-DD] | Picloxydinum [INN-Latin] | CHEBI:135768 | DB13607 | Picloxydinum | UNII-4YC2PY3AEU | N1,N4-Bis(N-(4-chlorophenyl)carbamimidoyl)piperazine-1,4-bis(carboximidamide) | Picloxidina [INN-Spanish] | Picloxydine | PICLOXYDINE [INN] | EINEC

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

Picloxydine is a heterocyclic biguanide with antibacterial and antiplaque activity.

In Vivo

0.4% Picloxydine produces a highly significant drop in the number of aerobic organisms. 0.4% Picloxydine is far more effective than 0.2% Picloxydine or chlorhexidine in reducing the total viable count of oral aerobic and anaerobic organisms . Picloxydine is also used in eye drops in the topical therapy of trachoma. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:Bacterial

Especificações

Sinónimos

PICLOXYDINE [WHO-DD] | Picloxydinum [INN-Latin] | CHEBI:135768 | DB13607 | Picloxydinum | UNII-4YC2PY3AEU | N1,N4-Bis(N-(4-chlorophenyl)carbamimidoyl)piperazine-1,4-bis(carboximidamide) | Picloxidina [INN-Spanish] | Picloxydine | PICLOXYDINE [INN] | EINEC

Especificações e pureza

≥98%

Mecanismos bioquímicos e fisiológicos

Picloxydine is a heterocyclic biguanide with antibacterial and antiplaque activity.

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

INHIBITOR

Pureza

≥98%

Nomes e identificadores

Sorrisos canónicos

C1CN(CCN1C(=NC(=NC2=CC=C(C=C2)Cl)N)N)C(=NC(=NC3=CC=C(C=C3)Cl)N)N

IUPAC Name

1-N',4-N'-bis[N'-(4-chlorophenyl)carbamimidoyl]piperazine-1,4-dicarboximidamide

InChIKey

YNCLPFSAZFGQCD-UHFFFAOYSA-N

INCHI

1S/C20H24Cl2N10/c21-13-1-5-15(6-2-13)27-17(23)29-19(25)31-9-11-32(12-10-31)20(26)30-18(24)28-16-7-3-14(22)4-8-16/h1-8H,9-12H2,(H4,23,25,27,29)(H4,24,26,28,30)

SMILES isoméricas

C1N(CCN(C1)/C(=N/C(=NC2=CC=C(C=C2)Cl)N)/N)/C(=N/C(=NC3=CC=C(C=C3)Cl)N)/N

CAS alternativo

5636-92-0

PubChem CID

5748610

Termos de entrada MeSH

1,1-(p-chlorophenylguanidinoformimidonyl)bis piperazine;picloxidine;picloxydine;picloxydine dihydrochloride;Vitabact

Peso molecular

475.38

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Halobenzenes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Halobenzenes
• Intermediate Tree Nodes: Not available
• Direct Parent: Chlorobenzenes
• Alternative Parents: Biguanides Piperazines Aryl chlorides Propargyl-type 1,3-dipolar organic compounds Carboximidamides Azacyclic compounds Organopnictogen compounds Organochlorides Imines Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Biguanide - Chlorobenzene - Aryl chloride - Aryl halide - 1,4-diazinane - Piperazine - Guanidine - Azacycle - Organoheterocyclic compound - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidamide - Imine - Organopnictogen compound - Organic nitrogen compound - Organohalogen compound - Organochloride - Organonitrogen compound - Hydrocarbon derivative - Aromatic heteromonocyclic compound
• Descrição: This compound belongs to the class of organic compounds known as chlorobenzenes. These are compounds containing one or more chlorine atoms attached to a benzene moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriedades químicas e físicas

• Solubilidade: DMSO : 11.36 mg/mL (23.90 mM; ultrasonic and warming and adjust pH to 5 with HCl and heat to 60°C)
• Peso molecular: 475.400 g/mol
• XLogP3: 1.800
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 474.156 Da
• Monoisotopic Mass: 474.156 Da
• Topological Polar Surface Area: 160.000 Ų
• Heavy Atom Count: 32
• Formal Charge: 0
• Complexity: 667.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 2
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 2
• Covalently-Bonded Unit Count: 1

Perguntas frequentes

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 5636-92-0, the molecular formula is C20H24Cl2N10, and the molecular weight is 475.38 g/mol. InChIKey YNCLPFSAZFGQCD-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.