Pitstop ® 1 , CAS No.1332879-51-2

CAS: 1332879-51-2 Cat. No.: P274823 Fórmula: C₁₉H₁₃N₂NaO₅S Peso molecular: 404.37 PubChem CID: 71483522

Synonyms

2-(4-Aminobenzyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-5-sulfonicacidsodiumsalt

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

Visão geral

Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Specifications

Sinónimos

2-(4-Aminobenzyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-5-sulfonicacidsodiumsalt

Mecanismos bioquímicos e fisiológicos

Novel, selective clathrin inhibitor. Competitively inhibits clathrin terminal domain (TD) to selectively inhibit clathrin mediated endocytosis (IC 50 = ~18 μM for inhibition of amphiphysin association of clathrin TD). Interferes with receptor mediated end

Condições de armazenamento de armazenamento

Store at 2-8°C,Desiccated

Enviado em

Wet ice

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Nomes e identificadores

• Sorrisos canónicos: C1=CC2=CC(=CC3=C2C(=C1)C(=O)N(C3=O)CC4=CC=C(C=C4)N)S(=O)(=O)[O-].[Na+]
• IUPAC Name: sodium;2-[(4-aminophenyl)methyl]-1,3-dioxobenzo[de]isoquinoline-5-sulfonate
• InChIKey: MKPPGLKJTZAXNE-UHFFFAOYSA-M
• INCHI: 1S/C19H14N2O5S.Na/c20-13-6-4-11(5-7-13)10-21-18(22)15-3-1-2-12-8-14(27(24,25)26)9-16(17(12)15)19(21)23;/h1-9H,10,20H2,(H,24,25,26);/q;+1/p-1
• SMILES isoméricas: C1=CC2=CC(=CC3=C2C(=C1)C(=O)N(C3=O)CC4=CC=C(C=C4)N)S(=O)(=O)[O-].[Na+]
• PubChem CID: 71483522
• Peso molecular: 404.37

Propriedades químicas e físicas

• Solubilidade: Soluble in water to 25 mM and in DMSO to 100 mM

Perguntas frequentes

How should this product be stored?

Store at 2–8 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1332879-51-2, the molecular formula is C19H13N2NaO5S, and the molecular weight is 404.37 g/mol. InChIKey MKPPGLKJTZAXNE-UHFFFAOYSA-M.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.