PK44 , CAS No.1017682-65-3

CAS: 1017682-65-3 Cat. No.: P1441921 PubChem CID: 46208486

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

PK44 (Compound 67) is a potent dipeptidyl peptidase IV ( DPP-IV ) inhibitor with an IC 50 value of 15.8 nM. PK44 is promising for research of diabetes.

Specifications

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

INHIBITOR

Nomes e identificadores

• Sorrisos canónicos: C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)CC(CC3=C4C=CC(=C(C4=NN3)F)F)N
• IUPAC Name: (3R)-3-amino-4-(6,7-difluoro-2H-indazol-3-yl)-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]butan-1-one
• InChIKey: LIPWZZYFIVYJSI-MRVPVSSYSA-N
• INCHI: 1S/C17H16F5N7O/c18-10-2-1-9-11(24-26-15(9)14(10)19)5-8(23)6-13(30)28-3-4-29-12(7-28)25-27-16(29)17(20,21)22/h1-2,8H,3-7,23H2,(H,24,26)/t8-/m1/s1
• SMILES isoméricas: C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=C4C=CC(=C(C4=NN3)F)F)N
• PubChem CID: 46208486

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Beta amino acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives
• Direct Parent: Beta amino acids and derivatives
• Alternative Parents: Triazolopyrazines Indazoles Aralkylamines Aryl fluorides Benzenoids Pyrazines Triazoles Tertiary carboxylic acid amides Heteroaromatic compounds Pyrazoles Tertiary amines Azacyclic compounds Hydrocarbon derivatives Alkyl fluorides Carbonyl compounds Monoalkylamines Organic oxides Organofluorides
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Beta amino acid or derivatives - Benzopyrazole - Indazole - Triazolopyrazine - Aralkylamine - Aryl fluoride - Aryl halide - Pyrazine - Benzenoid - 1,2,4-triazole - Triazole - Tertiary carboxylic acid amide - Pyrazole - Heteroaromatic compound - Azole - Tertiary amine - Carboxamide group - Azacycle - Organoheterocyclic compound - Hydrocarbon derivative - Organofluoride - Organohalogen compound - Primary aliphatic amine - Organic oxide - Organonitrogen compound - Carbonyl group - Organic oxygen compound - Organic nitrogen compound - Organooxygen compound - Alkyl halide - Alkyl fluoride - Primary amine - Amine - Aromatic heteropolycyclic compound
• Descrição: This compound belongs to the class of organic compounds known as beta amino acids and derivatives. These are amino acids having a (-NH2) group attached to the beta carbon atom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Perguntas frequentes

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1017682-65-3. InChIKey LIPWZZYFIVYJSI-MRVPVSSYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.