The store will not work correctly when cookies are disabled.
O JavaScript parece estar desativado no seu browser. Para usufruir da melhor experiência no nosso site, certifique-se que ativa o JavaScript no seu browser.
· · COA & SDS Disponível para todos os produtos · Envio no mesmo dia em itens em estoque PNU 74654 - 10mM in DMSO , CAS No.113906-27-7
Disponível para encomenda
GRADE & PURITY 10mM in DMSO
Synonyms
HMS3413P04 | HY-101130 | PNU74654 | PNU-74654 | J-003040 | NSC755984 | NSC-755984 | CCG-208115 | N-[(E)-(5-Methylfuran-2-yl)methylideneamino]-2-phenoxybenzamide | SCHEMBL3514174 | BDBM50436058 | AC-33054 | PNU 74654 | 2-Phenoxybenzoic acid-[(5-methyl-2-fu
Shipped In
Dry ice packs + Cold packs
🧪
Why this grade 10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
🌡
Storage & shipping Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
📋
Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
📚
Literature proof Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Visão geral
application：
PNU-74654 has been used:
as a β-catenin signaling inhibitor to study its effects on the funnel cartilage differentiation in Sepia sp. embryos
as a Wnt signaling inhibitor to study its effects on glycogen synthase kinase 3β (GSK-3β) inhibition in prostate cancer cell lines
as a Wnt signaling inhibitor to study its effects on leptin-induced cell proliferation in breast cancer cells
Specifications Sinónimos
HMS3413P04 | HY-101130 | PNU74654 | PNU-74654 | J-003040 | NSC755984 | NSC-755984 | CCG-208115 | N-[(E)-(5-Methylfuran-2-yl)methylideneamino]-2-phenoxybenzamide | SCHEMBL3514174 | BDBM50436058 | AC-33054 | PNU 74654 | 2-Phenoxybenzoic acid-[(5-methyl-2-fu
Especificações e pureza
10mM in DMSO
Mecanismos bioquímicos e fisiológicos
Wnt signaling pathway blocker. Inhibits Wnt/β-catenin pathway. Blocks the protein-protein interaction between β-catenin and TCF. Antitumor effects.PNU-74654 inhibits the Wnt-β catenin pathway by blocking the interaction between β-catenin and TCF (T cell f
Condições de armazenamento de armazenamento
Store at -80°C
Enviado em
Dry ice packs + Cold packs
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Nomes e identificadores Sorrisos canónicos
CC1=CC=C(O1)C=NNC(=O)C2=CC=CC=C2OC3=CC=CC=C3
IUPAC Name
N-[(E)-(5-methylfuran-2-yl)methylideneamino]-2-phenoxybenzamide
InChIKey
JJEDWBQZCRESJL-DEDYPNTBSA-N
INCHI
1S/C19H16N2O3/c1-14-11-12-16(23-14)13-20-21-19(22)17-9-5-6-10-18(17)24-15-7-3-2-4-8-15/h2-13H,1H3,(H,21,22)/b20-13+
SMILES isoméricas
CC1=CC=C(O1)/C=N/NC(=O)C2=CC=CC=C2OC3=CC=CC=C3
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Classe Benzene and substituted derivatives Subclass Diphenylethers Intermediate Tree Nodes Not available Direct Parent Diphenylethers Alternative Parents Diarylethers Benzoic acids and derivatives Phenoxy compounds Phenol ethers Benzoyl derivatives Heteroaromatic compounds Furans Oxacyclic compounds Carboxylic acids and derivatives Organonitrogen compounds Organic oxides Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents Diphenylether - Diaryl ether - Benzoic acid or derivatives - Benzoyl - Phenoxy compound - Phenol ether - Heteroaromatic compound - Furan - Oxacycle - Organoheterocyclic compound - Ether - Carboxylic acid derivative - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxygen compound - Organic oxide - Aromatic heteromonocyclic compound Descrição This compound belongs to the class of organic compounds known as diphenylethers. These are aromatic compounds containing two benzene rings linked to each other through an ether group. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estrutura 3D Alvos associados (humanos) Alvos associados (não humanos) Mecanismos de ação Certificados（CoA,COO,BSE/TSE e Mapa de Análise) Propriedades químicas e físicas Peso molecular 320.300 g/mol XLogP3 4.200 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 4 Rotatable Bond Count 5 Exact Mass 320.116 Da Monoisotopic Mass 320.116 Da Topological Polar Surface Area 63.800 Ų Heavy Atom Count 24 Formal Charge 0 Complexity 434.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 1 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 1 Covalently-Bonded Unit Count 1
Citations of This Product Calculadoras de soluções Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator Revisões
We use cookies to ensure the website functions properly and, where permitted, to improve your experience. You can manage your preferences at any time in Settings. Learn more in our
Cookie Policy. Definições Concordo com tudo Decline
Shall we send you a message when we have discounts available?
Remind me later Autorizar
Thank you! Please check your email inbox to confirm.
Oops! Notifications are disabled.
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.
K2411564