Polysucrose - 1000 kDa , CAS No.26873-85-8

CAS: 26873-85-8 Cat. No.: P292487 EC Number: 608-012-3 PubChem CID: 88330506

GRADE & PURITY 1000 kDa

Synonyms

26873-85-8|2-(chloromethyl)oxirane;(2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol|SCHEMBL8603704|Sucrose-epichlorohydrin copolymer|AKOS040757967|A852961||A-D-Glucopyranoside, |A-D-f

Storage

Protected from light,Store at -20°C,Argon charged,Desiccated

Shipped In

Ice chest + Ice pads

Overview

Polysucroses (renamed from Ficoll™) are formed by copolymerization of sucrose with epichlorohydrin. The molecules are highly branched, and the high content of hydroxyl groups leads to very good solubility in aqueous media. Polysucroses behave as an ideal neutral sphere and displays excellent biocompatibility. Polysucrose does not contain any ionized groups, so it compatible under physiological conditions. Polysucrose is more sensitive to acid than dextran so that care must be taken when working at acid pH.Properties of the polysucroses include:All batches are checked for molecular weight, degree of substitution and loss on drying. Aladdin produce Polysucrose from 20 kDa to 1000 kDa. Polysucrose is provided as a dry powder and is extremely hydrophilic.

Structure

Polysucrose is a polymer synthesised by cross-linking sucrose with epichlorohydrin. Polysucrose has a more spherical structure and is less flexible compared to dextran.

Application

Polysucrose behaves as an ideal neutral sphere and it displays excellent biocompatibility.

Specifications

Synonyms

26873-85-8 | 2-(chloromethyl)oxirane;(2R, 3R, 4S, 5S, 6R)-2-[(2S, 3S, 4S, 5R)-3, 4-dihydroxy-2, 5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3, 4, 5-triol | SCHEMBL8603704 | Sucrose-epichlorohydrin copolymer | AKOS040757967 | A852961 | | A-D-Glucopyranoside, | A-D-f

Specifications & Purity

1000 kDa

Storage

Protected from light, Store at -20°C, Argon charged, Desiccated

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Canonical Smiles: C1C(O1)CCl.C(C1C(C(C(C(O1)OC2(C(C(C(O2)CO)O)O)CO)O)O)O)O
• IUPAC Name: 2-(chloromethyl)oxirane;(2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
• InChIKey: IACFXVUNKCXYJM-AKSHDPDZSA-N
• INCHI: 1S/C12H22O11.C3H5ClO/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12;4-1-3-2-5-3/h4-11,13-20H,1-3H2;3H,1-2H2/t4-,5-,6-,7-,8+,9-,10+,11-,12+;/m1./s1
• Isomeric SMILES: C1C(O1)CCl.C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@]2([C@H]([C@@H]([C@H](O2)CO)O)O)CO)O)O)O)O
• WGK Germany: 3
• PubChem CID: 88330506

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Class Organooxygen compounds
      • Subclass Carbohydrates and carbohydrate conjugates
        • Level5 Glycosyl compounds
          • Level6 O-glycosyl compounds

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Class: Organooxygen compounds
• Subclass: Carbohydrates and carbohydrate conjugates
• Intermediate Tree Nodes: Glycosyl compounds
• Direct Parent: O-glycosyl compounds
• Alternative Parents: Disaccharides C-glycosyl compounds Ketals Oxanes Oxolanes Secondary alcohols Polyols Oxacyclic compounds Epoxides Dialkyl ethers Primary alcohols Organochlorides Hydrocarbon derivatives Alkyl chlorides
• Molecular Framework: Not available
• Substituents: C-glycosyl compound - Disaccharide - O-glycosyl compound - Ketal - Oxane - Oxolane - Secondary alcohol - Acetal - Oxacycle - Organoheterocyclic compound - Polyol - Dialkyl ether - Ether - Oxirane - Hydrocarbon derivative - Organohalogen compound - Organochloride - Primary alcohol - Alkyl halide - Alkyl chloride - Alcohol - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as o-glycosyl compounds. These are glycoside in which a sugar group is bonded through one carbon to another group via a O-glycosidic bond.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Polysucrose dissolves readily in water.
• Sensitivity: Light sensitive,Moisture sensitive
• Specific Rotation[α]: [α]20/D 56.5°, c = 1% (w/v) in water
• Molecular Weight: 434.820 g/mol
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 6
• Exact Mass: 434.119 Da
• Monoisotopic Mass: 434.119 Da
• Topological Polar Surface Area: 202.000 Ų
• Heavy Atom Count: 28
• Formal Charge: 0
• Complexity: 433.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 9
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

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