Cloridrato de Prasugrel - ≥99% , Purinergic receptor P2Y12 antagonist, CAS No.389574-19-0, Purinergic receptor P2Y12 antagonist

CAS: 389574-19-0 Cat. No.: P303623 Fórmula: C₂₀H₂₁ClFNO₃S Peso molecular: 409.9 Número CE: 627-126-4 PubChem CID: 10158453

GRADE & PURITY ≥99%

Synonyms

CCG-268764 | PRASUGREL HYDROCHLORIDE [USP MONOGRAPH] | rac-5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridin-2-yl acetate hydrochloride | PRASUGREL HYDROCHLORIDE (EP MONOGRAPH) | PRASUGREL HYDROCHLORIDE [MART.] | Tox21

Storage

Armazenar a -20°C

Shipped In

Arca de gelo + almofadas de gelo

Visão geral

Descrição do produto:

O cloridrato de prasugrel (cloridrato PCR 4099), uma tienopiridina e um pró-fármaco, inibe a função plaquetária. O cloridrato de prasugrel é um potente antagonista dos receptores P2Y12, ativo por via oral, e inibe a agregação plaquetária induzida pelo ADP.

Specifications

Sinónimos

CCG-268764 | PRASUGREL HYDROCHLORIDE [USP MONOGRAPH] | rac-5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridin-2-yl acetate hydrochloride | PRASUGREL HYDROCHLORIDE (EP MONOGRAPH) | PRASUGREL HYDROCHLORIDE [MART.] | Tox21

Especificações e pureza

≥99%

Condições de armazenamento de armazenamento

Armazenar a -20°C

Enviado em

Arca de gelo + almofadas de gelo

Tipo de ação

ANTAGONIST

Mecanismo de ação

Purinergic receptor P2Y12 antagonist

Pureza

≥99%

Nomes e identificadores

Pubchem Sid

504765291

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504765291

Sorrisos canónicos

CC(=O)OC1=CC2=C(S1)CCN(C2)C(C3=CC=CC=C3F)C(=O)C4CC4.Cl

IUPAC Name

[5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] acetate;hydrochloride

InChIKey

JALHGCPDPSNJNY-UHFFFAOYSA-N

INCHI

1S/C20H20FNO3S.ClH/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21;/h2-5,10,13,19H,6-9,11H2,1H3;1H

SMILES isoméricas

CC(=O)OC1=CC2=C(S1)CCN(C2)C(C3=CC=CC=C3F)C(=O)C4CC4.Cl

PubChem CID

10158453

Peso molecular

409.9

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Thienopyridines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Thienopyridines
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Thienopyridines
• Alternative Parents: 2,3,5-trisubstituted thiophenes Aralkylamines Fluorobenzenes Pyridines and derivatives Aryl fluorides Alpha-amino ketones Heteroaromatic compounds Trialkylamines Carboxylic acid esters Amino acids and derivatives Azacyclic compounds Monocarboxylic acids and derivatives Hydrocarbon derivatives Organic oxides Organofluorides Organopnictogen compounds Hydrochlorides
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Thienopyridine - 2,3,5-trisubstituted thiophene - Halobenzene - Aralkylamine - Fluorobenzene - Pyridine - Benzenoid - Monocyclic benzene moiety - Aryl halide - Aryl fluoride - Heteroaromatic compound - Thiophene - Alpha-aminoketone - Carboxylic acid ester - Ketone - Amino acid or derivatives - Tertiary aliphatic amine - Tertiary amine - Carboxylic acid derivative - Azacycle - Monocarboxylic acid or derivatives - Organonitrogen compound - Organooxygen compound - Hydrochloride - Amine - Organic nitrogen compound - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organohalogen compound - Organofluoride - Aromatic heteropolycyclic compound
• Descrição: This compound belongs to the class of organic compounds known as thienopyridines. These are heterocyclic compounds containing a thiophene ring fused to a pyridine ring. Thiophene is 5-membered ring consisting of four carbon atoms and one sulfur atom. Pyridine is a 6-membered ring consisting of five carbon atoms and one nitrogen center.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mecanismos de ação

Propriedades químicas e físicas

• Sensibilidade: light & Moisture sensitive
• Ponto de inflamação (°C): 252.3℃
• Ponto de ebulição (°C): 493.5℃ at 760 mmHg
• Peso molecular: 409.900 g/mol
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 6
• Exact Mass: 409.091 Da
• Monoisotopic Mass: 409.091 Da
• Topological Polar Surface Area: 74.900 Ų
• Heavy Atom Count: 27
• Formal Charge: 0
• Complexity: 555.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

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