Praxadine , CAS No.4023-00-1

CAS: 4023-00-1 Cat. No.: P668706 Fórmula: C₄H₆N₄ Peso molecular: 110.12 PubChem CID: 2734673

Synonyms

1H-pyrazole-1-carboximidamide | Praxadine | Pyrazole-1-carboxamidine | pyrazole-1-carboximidamide | 1H-Pyrazole-1-carboxamidine | 12L58GX4AS | Praxadine [INN:DCF] | NCGC00165996-01 | UNII-12L58GX4AS | SR-01000945145 | 1-amidinopyrazole | PRAXADINE [INN] |

Storage

Room temperature

Specifications

Sinónimos

1H-pyrazole-1-carboximidamide | Praxadine | Pyrazole-1-carboxamidine | pyrazole-1-carboximidamide | 1H-Pyrazole-1-carboxamidine | 12L58GX4AS | Praxadine [INN:DCF] | NCGC00165996-01 | UNII-12L58GX4AS | SR-01000945145 | 1-amidinopyrazole | PRAXADINE [INN] |

Condições de armazenamento de armazenamento

Room temperature

Propriedades do produto

• ALogP: -0.4

Nomes e identificadores

• Sorrisos canónicos: C1=CN(N=C1)C(=N)N
• IUPAC Name: pyrazole-1-carboximidamide
• InChIKey: UCQFSGCWHRTMGG-UHFFFAOYSA-N
• INCHI: 1S/C4H6N4/c5-4(6)8-3-1-2-7-8/h1-3H,(H3,5,6)
• SMILES isoméricas: C1=CN(N=C1)C(=N)N
• PubChem CID: 2734673
• Peso molecular: 110.12

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Azoles
      • Subclass Pyrazoles

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Azoles
• Subclass: Pyrazoles
• Intermediate Tree Nodes: Not available
• Direct Parent: Pyrazoles
• Alternative Parents: Heteroaromatic compounds Carboximidamides Azacyclic compounds Organopnictogen compounds Imines Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Heteroaromatic compound - Pyrazole - Azacycle - Carboximidamide - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Imine - Aromatic heteromonocyclic compound
• Descrição: This compound belongs to the class of organic compounds known as pyrazoles. These are compounds containing a pyrazole ring, which is a five-member aromatic ring with two nitrogen atoms (at positions 1 and 2) and three carbon atoms.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Alvos associados (humanos)

NOS1 Tchem Nitric oxide synthase, brain (1 Activities)

Discover Target: NOS1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Propriedades químicas e físicas

• Peso molecular: 110.120 g/mol
• XLogP3: -0.400
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 110.059 Da
• Monoisotopic Mass: 110.059 Da
• Topological Polar Surface Area: 67.700 Ų
• Heavy Atom Count: 8
• Formal Charge: 0
• Complexity: 100.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referências

1. Shaojun Yu, Jinrong Zheng, Haiting Xie, Qun Deng, Jianwei Wang, Jian Chen, Haitao Zhou, Jun Wang.  (2024)  Biocompatible Hydrogel Nanoparticles with Lysosomal Escape Properties for the Delivery of siRNA for the Gene Therapy of Colorectal Carcinoma.  ACS Applied Nano Materials,      [PMID:] [10.1021/acsanm.4c00466]

Perguntas frequentes

How should this product be stored?

Store at room temperature.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 4023-00-1, the molecular formula is C4H6N4, and the molecular weight is 110.12 g/mol. InChIKey UCQFSGCWHRTMGG-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.