Propranolol hydrochloride - Moligand™, ≥99% , Beta-2 adrenergic receptor antagonist, CAS No.318-98-9, Beta-2 adrenergic receptor antagonist

Name: Propranolol hydrochloride - Moligand™, ≥99% , Beta-2 adrenergic receptor antagonist, CAS No.318-98-9, Beta-2 adrenergic receptor antagonist
SKU: P276602
Availability: InStock

CAS: 318-98-9 Cat. No.: P276602 Fórmula: C₁₆H₂₁NO₂·HCl Peso molecular: 295.81 Número CE: 206-268-7 PubChem CID: 62882

19 Citations COA

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Propranolol hydrochloride - Moligand™, ≥99% CAS No(318-98-9) by Aladdin Scientific

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Disponível para encomenda

GRADE & PURITY Moligand™ ? ≥99%

Synonyms

Storage

Store at -20°C,Argon charged,Desiccated

Shipped In

Ice chest + Ice pads

Visão geral Specifications Nomes e identificadores Documentation Advanced Data Taxonomic Classification Estrutura 3D Alvos associados (humanos) Alvos associados (não humanos) Mecanismos de ação Certificados（CoA,COO,BSE/TSE e Mapa de Análise) Propriedades químicas e físicas FAQs e artigos Citations of This Product Calculadoras de soluções Revisões

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Why this grade

Moligand™, ≥99% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C,Argon charged,Desiccated Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 19 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Visão geral

Propranolol hydrochloride is a nonselective and BBB-permeableβ-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively. Propranolol hydrochloride inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM. Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy.

Specifications

Sinónimos

Especificações e pureza

Moligand™, ≥99%

Condições de armazenamento de armazenamento

Store at -20°C,Argon charged,Desiccated

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Grau

Moligand™

Tipo de ação

ANTAGONIST

Mecanismo de ação

Beta-2 adrenergic receptor antagonist

Pureza

≥99%

Nomes e identificadores

Pubchem Sid

488183616

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488183616

Sorrisos canónicos

CC(C)NCC(COC1=CC=CC2=CC=CC=C21)O.Cl

IUPAC Name

1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol;hydrochloride

InChIKey

ZMRUPTIKESYGQW-UHFFFAOYSA-N

INCHI

1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H

SMILES isoméricas

CC(C)NCC(COC1=CC=CC2=CC=CC=C21)O.Cl

CAS alternativo

3506-09-0

PubChem CID

62882

Peso molecular

295.81

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Classe Naphthalenes

Kingdom	Organic compounds
Superclass	Benzenoids
Classe	Naphthalenes
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Naphthalenes
Alternative Parents	Alkyl aryl ethers Secondary alcohols 1,2-aminoalcohols Dialkylamines Organopnictogen compounds Hydrochlorides Hydrocarbon derivatives
Molecular Framework	Aromatic homopolycyclic compounds
Substituents	Naphthalene - Alkyl aryl ether - 1,2-aminoalcohol - Secondary alcohol - Secondary aliphatic amine - Ether - Secondary amine - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Hydrochloride - Hydrocarbon derivative - Organopnictogen compound - Amine - Organic oxygen compound - Alcohol - Aromatic homopolycyclic compound
Descrição	This compound belongs to the class of organic compounds known as naphthalenes. These are compounds containing a naphthalene moiety, which consists of two fused benzene rings.
External Descriptors	hydrochloride
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Estrutura 3D

Alvos associados (humanos)

ABL1 Tclin Tyrosine-protein kinase ABL (18331 Activities)

Discover Target: ABL1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)

Discover Target: ADRB2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)

Discover Target: ADRB1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)

Discover Target: ADRA2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)

Discover Target: TSHR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AGTR1 Tclin Type-1 angiotensin II receptor (5176 Activities)

Discover Target: AGTR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)

Discover Target: PPARG

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KCNH2 Tclin HERG (29587 Activities)

Discover Target: KCNH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GSK3B Tclin Glycogen synthase kinase-3 beta (11785 Activities)

Discover Target: GSK3B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TRPV1 Tclin Vanilloid receptor (8273 Activities)

Discover Target: TRPV1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CSNK1D Tchem Casein kinase I delta (4546 Activities)

Discover Target: CSNK1D

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)

Discover Target: ALOX15B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NR1H4 Tclin Bile acid receptor FXR (6228 Activities)

Discover Target: NR1H4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

S1PR1 Tclin Sphingosine 1-phosphate receptor Edg-1 (5806 Activities)

Discover Target: S1PR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CDK2 Tchem Cyclin-dependent kinase 2 (9050 Activities)

Discover Target: CDK2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)

Discover Target: GLP1R

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

C5AR1 Tclin C5a anaphylatoxin chemotactic receptor (2677 Activities)

Discover Target: C5AR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AURKA Tchem Serine/threonine-protein kinase Aurora-A (10240 Activities)

Discover Target: AURKA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Homo sapiens (32628 Activities)

Lot Number	Certificate Type	Data	Item
B23111130	Certificate of Analysis	Jul 03, 2026	P276602
A2425285	Certificate of Analysis	May 20, 2026	P276602
A2425289	Certificate of Analysis	May 20, 2026	P276602
A2425304	Certificate of Analysis	May 20, 2026	P276602
A2425333	Certificate of Analysis	May 20, 2026	P276602
I2610116	Certificate of Analysis	Apr 20, 2026	P276602
D2630296	Certificate of Analysis	Apr 20, 2026	P276602
D2630294	Certificate of Analysis	Apr 20, 2026	P276602
D2630293	Certificate of Analysis	Apr 20, 2026	P276602
D2630279	Certificate of Analysis	Apr 20, 2026	P276602
B23111159	Certificate of Analysis	Apr 03, 2026	P276602
B23111158	Certificate of Analysis	Apr 03, 2026	P276602
D2507584	Certificate of Analysis	Jan 20, 2026	P276602
D2507648	Certificate of Analysis	Jan 20, 2026	P276602
A2510135	Certificate of Analysis	Oct 13, 2025	P276602
K2511018	Certificate of Analysis	Mar 22, 2025	P276602
L2515032	Certificate of Analysis	Mar 22, 2025	P276602
D2507647	Certificate of Analysis	Mar 22, 2025	P276602
D2507646	Certificate of Analysis	Mar 22, 2025	P276602
A2425281	Certificate of Analysis	Oct 18, 2024	P276602
A2425283	Certificate of Analysis	Oct 18, 2024	P276602
A2425279	Certificate of Analysis	Oct 18, 2024	P276602
C2518454	Certificate of Analysis	Jul 23, 2024	P276602
F2421333	Certificate of Analysis	Apr 01, 2024	P276602
F2421334	Certificate of Analysis	Apr 01, 2024	P276602
A2506160	Certificate of Analysis	Apr 01, 2024	P276602
A2506159	Certificate of Analysis	Apr 01, 2024	P276602
B23111145	Certificate of Analysis	Nov 17, 2023	P276602
B23111129	Certificate of Analysis	Nov 17, 2023	P276602
B23111111	Certificate of Analysis	Nov 17, 2023	P276602
H2219397	Certificate of Analysis	Jun 06, 2023	P276602
H2219398	Certificate of Analysis	Jun 06, 2023	P276602
H2219399	Certificate of Analysis	Jun 06, 2023	P276602
B23111105	Certificate of Analysis	Jan 31, 2023	P276602
C2204018	Certificate of Analysis	Nov 13, 2021	P276602
F2222490	Certificate of Analysis	Nov 13, 2021	P276602

Solubilidade	Soluble in water to 100 mM
Sensibilidade	Moisture sensitive
Ponto de fusão (°C)	163-165°C
Peso molecular	295.800 g/mol
XLogP3
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	6
Exact Mass	295.134 Da
Monoisotopic Mass	295.134 Da
Topological Polar Surface Area	41.500 Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	257.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

Propranolol hydrochloride - Moligand™, ≥99% , Beta-2 adrenergic receptor antagonist, CAS No.318-98-9, Beta-2 adrenergic receptor antagonist

Storage & shipping

Quality documents

Literature proof

Visão geral

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Avaliações dos Clientes

📚 Citations by Application

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