for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Visão geral
PROTAC KSP-IN-1 (Compound 21) is a PROTAC Degrader for kinesin spindle protein ( KSP ), that degrades KSP in HCT-116 with DC 50 of 114.8 nM. PROTAC KSP-IN-1 inhibits the proliferation of HCT-116 with IC 50 of 10 nM, arrests the cell cycle of HCT-116 at G2/M phase, and induces apoptosis in HCT-116. PROTAC KSP-IN-1 exhibits antitumor efficacy in mouse model. (Blue: Ligand for E3 Ligase Cereblon ; Blank: Linker ; Pink: Target Protein Ligand )
Specifications
Condições de armazenamento de armazenamento
Store at -20°C
Enviado em
Ice chest + Ice pads
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Tipo de ação
DEGRADER
Nomes e identificadores
Peso molecular
858.01
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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