10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Visão geral
Rapanone is a natural benzoquinone. Rapanone exhibits a broad spectrum of biological actions, including anti-tumor, antioxidant, anti-inflammatory, antibacterial and antiparasitic. Rapanone also is a potent and selective human synovial PLA 2 inhibitor, with an IC 50 of 2.6 μM.
In Vitro
Rapanone (10-40 μM; 24 h) inhibits the cell viability, with IC 50 s of 35.58 μM and 27.89 μM for primary rats hepatocytes and HepG2 cells, respectively. Rapanone (10-40 μM; 24 h) induces a concentration-dependent mitochondrial membrane potential dissipation, ATP depletion, hydrogen peroxide generation and, phosphatidyl serine externalization in HepG2 cells. Rapanone inhibits electron transport at Complex III and promotes mitochondrial dysfunction. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Rapanone (2.5-10 mg/kg; i.p.) exhibits anti-inflammatory effects in the carrageenan paw oedema model in mice. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Specifications
Especificações e pureza
10mM in DMSO
Mecanismos bioquímicos e fisiológicos
Rapanone is a natural benzoquinone. Rapanone exhibits a broad spectrum of biological actions, including anti-tumor, antioxidant, anti-inflammatory, antibacterial and antiparasitic. Rapanone also is a potent and selective human synovial PLA 2 inhibitor, wi
Condições de armazenamento de armazenamento
Store at -80°C
Enviado em
Dry ice packs + Cold packs
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Nomes e identificadores
SMILES isoméricas
CCCCCCCCCCCCCC1=C(C(=O)C=C(C1=O)O)O
Peso molecular
322.44
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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