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· · COA & SDS Disponível para todos os produtos · Envio no mesmo dia em itens em estoque Remodelin - Moligand™, ≥99%(HPLC) , CAS No.949912-58-7
Disponível para encomenda
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(HPLC) Synonyms
4-[2-(2-CYCLOPENTYLIDENEHYDRAZIN-1-YL)-1,3-THIAZOL-4-YL]BENZONITRILE | BCP11087 | NCGC00384186-14 | A900145 | GTPL8102 | SCHEMBL17144586 | BDBM50326653 | Remodelin | 4-[2-(2-cyclopentylidenehydrazinyl)-1,3-thiazol-4-yl]benzonitrile | EX-A1315 | ZMB91258 |
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥99%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Visão geral Product description：
Remodelin is an effective and specific inhibitor of the acetyl-transferase protein NAT10.
Specifications Sinónimos
4-[2-(2-CYCLOPENTYLIDENEHYDRAZIN-1-YL)-1,3-THIAZOL-4-YL]BENZONITRILE | BCP11087 | NCGC00384186-14 | A900145 | GTPL8102 | SCHEMBL17144586 | BDBM50326653 | Remodelin | 4-[2-(2-cyclopentylidenehydrazinyl)-1,3-thiazol-4-yl]benzonitrile | EX-A1315 | ZMB91258 |
Especificações e pureza
Moligand™, ≥99%(HPLC)
Mecanismos bioquímicos e fisiológicos
N-acetyltransferase 10 (NAT10) inhibitor. Improves nuclear shape in HGPS (Hutchinson-Gilford progeria syndrome) cells and lamin A/C depleted cells.
Condições de armazenamento de armazenamento
Store at -20°C
Enviado em
Ice chest + Ice pads
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Nomes e identificadores Pubchem Sid 528766942 Sorrisos canónicos C1CCC(=NNC2=NC(=CS2)C3=CC=C(C=C3)C#N)C1 IUPAC Name 4-[2-(2-cyclopentylidenehydrazinyl)-1,3-thiazol-4-yl]benzonitrile InChIKey XAEJIFARBQJLML-UHFFFAOYSA-N INCHI 1S/C15H14N4S/c16-9-11-5-7-12(8-6-11)14-10-20-15(17-14)19-18-13-3-1-2-4-13/h5-8,10H,1-4H2,(H,17,19) SMILES isoméricas C1CCC(=NNC2=NC(=CS2)C3=CC=C(C=C3)C#N)C1 CAS alternativo 949912-58-7 PubChem CID 44442376 Termos de entrada MeSH 4-(4-cyanophenyl)-2-(2-cyclopentylidenehydrazinyl)thiazole;remodelin Peso molecular 282.36
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Classe Benzene and substituted derivatives Subclass Benzonitriles Intermediate Tree Nodes Not available Direct Parent Benzonitriles Alternative Parents 2,4-disubstituted thiazoles Heteroaromatic compounds Nitriles Hydrazones Azacyclic compounds Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents Benzonitrile - 2,4-disubstituted 1,3-thiazole - Heteroaromatic compound - Thiazole - Azole - Azacycle - Organoheterocyclic compound - Nitrile - Carbonitrile - Hydrazone - Organic nitrogen compound - Cyanide - Hydrocarbon derivative - Organonitrogen compound - Aromatic heteromonocyclic compound Descrição This compound belongs to the class of organic compounds known as benzonitriles. These are organic compounds containing a benzene bearing a nitrile substituent. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estrutura 3D Alvos associados (humanos) Alvos associados (não humanos) Mecanismos de ação Certificados（CoA,COO,BSE/TSE e Mapa de Análise) Propriedades químicas e físicas Solubilidade Solvent:DMSO, Max Conc. mg/mL: 28.24, Max Conc. mM: 100 Peso molecular 282.400 g/mol XLogP3 3.300 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 5 Rotatable Bond Count 3 Exact Mass 282.094 Da Monoisotopic Mass 282.094 Da Topological Polar Surface Area 89.300 Ų Heavy Atom Count 20 Formal Charge 0 Complexity 397.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
Citations of This Product Referências 1. Yunhong Zhang, Zhen Zhang, Xinkui Liu, Chu Chu, Xiaoyan Yu, Qiaoqiao Han, Wei Li, Tingting Zhang, Huiyan Zu, Nannan Fan, Ran Wei, Feifei Shi, Fang Li, Fei Xu, Bin Wang, Xia Li. (2025) NAT10-Mediated ac4C-Modification Exacerbates Ferroptosis by Stabilizing HMOX1 in Deep Vein Thrombosis. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, [PMID:41467352 ] [10.1161/ATVBAHA.125.323986 ]
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