≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Remodelin hydrobromide Remodelin hydrobromide (HBr) is a potent acetyl-transferase NAT10 inhibitor.
Targets
NAT10
In vitro
Remodelin, via inhibition of NAT10, mediates nuclear shape rescue of LMNA depleted cells by microtubule reorganization, and improves nuclear shape and fitness of HGPS cells. Remodelin may thus provide opportunities for alleviating dystrophic and premature-ageing diseases.
| ALogP | 4.031 |
|---|---|
| Contagem HBD | 1 |
| Ligação rotativa | 3 |
| Pubchem Sid | 528766941 |
|---|---|
| Sorrisos canónicos | C1CCC(=NNC2=NC(=CS2)C3=CC=C(C=C3)C#N)C1.Br |
| IUPAC Name | 4-[2-(2-cyclopentylidenehydrazinyl)-1,3-thiazol-4-yl]benzonitrile;hydrobromide |
| InChIKey | XNWBCMSPDCSWSD-UHFFFAOYSA-N |
| INCHI | 1S/C15H14N4S.BrH/c16-9-11-5-7-12(8-6-11)14-10-20-15(17-14)19-18-13-3-1-2-4-13;/h5-8,10H,1-4H2,(H,17,19);1H |
| SMILES isoméricas | C1CCC(=NNC2=NC(=CS2)C3=CC=C(C=C3)C#N)C1.Br |
| PubChem CID | 86280479 |
| Peso molecular | 363.28 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Classe | Benzene and substituted derivatives |
| Subclass | Benzonitriles |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Benzonitriles |
| Alternative Parents | 2,4-disubstituted thiazoles Heteroaromatic compounds Nitriles Hydrazones Azacyclic compounds Hydrocarbon derivatives Hydrobromides |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Benzonitrile - 2,4-disubstituted 1,3-thiazole - Azole - Thiazole - Heteroaromatic compound - Organoheterocyclic compound - Nitrile - Carbonitrile - Hydrazone - Azacycle - Hydrobromide - Organonitrogen compound - Cyanide - Organic nitrogen compound - Hydrocarbon derivative - Aromatic heteromonocyclic compound |
| Descrição | This compound belongs to the class of organic compounds known as benzonitriles. These are organic compounds containing a benzene bearing a nitrile substituent. |
| External Descriptors | Not available |
| Solubilidade | Solubility (25°C) In vitro DMSO: 72 mg/mL warmed with 50ºC Water: bath (198.19 mM); Water: Insoluble; Ethanol: Insoluble; |
|---|---|
| Sensibilidade | Moisture sensitive. |
| DMSO (mg/mL) Solubilidade máxima | 72 |
| DMSO (mM) Solubilidade máxima | 198.1942303 |
| Água (mg/mL) Solubilidade máxima | ＜1 |
| Peso molecular | 363.300 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 3 |
| Exact Mass | 362.02 Da |
| Monoisotopic Mass | 362.02 Da |
| Topological Polar Surface Area | 89.300 Ų |
| Heavy Atom Count | 21 |
| Formal Charge | 0 |
| Complexity | 397.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |
G2209339