RF9 hydrochloride - 10mM in DMSO , CAS No.R661629(DMSO)

CAS: R661629(DMSO) Cat. No.: R661629 Fórmula: C₂₆H₃₉ClN₆O₃ Peso molecular: 519.08

GRADE & PURITY 10mM in DMSO

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral

RF9 hydrochloride is a potent and selective Neuropeptide FF receptor antagonist, with K i values of 58 and 75 nM for hNPFF1R and hNPFF2R , respectively.

IC50& Target:hNPFF1R 58 nM (Ki) hNPFF2R 75 nM (Ki)

In Vitro:RF9 (10 μM) pretrement completely blocks NPFF induced neurite outgrowth of Neuro 2A cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo:RF9 (0.1mg/kg, s.c. ) with heroin coadministration prevents heroin-induced delayed hyperalgesia and tolerance. RF9 (10 μg) infused alone does not result in a significant alteration of MAP or heart rate. Conversely, MAP and heart rate increases evoke

Biological Activity:RF9 hydrochloride is a potent and selective Neuropeptide FF receptor antagonist, with K i values of 58 and 75 nM for hNPFF1R and hNPFF2R , respectively .

Specifications

Especificações e pureza

10mM in DMSO

Condições de armazenamento de armazenamento

Desiccated,Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Nomes e identificadores

Sorrisos canónicos

NC(C(CC1=CC=CC=C1)NC([C@H](CCCNC(N)=N)NC(C23C[C@H](C4)CC(C[C@@H]4C3)C2)=O)=O)=O.Cl

Peso molecular

519.08

Perguntas frequentes

How should this product be stored?

Store at ?80 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is R661629(DMSO), the molecular formula is C26H39ClN6O3, and the molecular weight is 519.08 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.