≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Visão geral
RG-13022 is a Tyrosine kinase tyrphostin. Reports indicate that RG-13022 suppresses epidermal growth factor (EGF)-stimulated cancer cell proliferation in cancer cell studies. Additionally, RG-13022 has been described to inhibit EGF, platelet-dervied growth (PDGF) signaling, and PDGF enhanced DNA synthesis. RG-13022 is an inhibitor of EGFR and PDGFR.
This compound belongs to the class of organic compounds known as dimethoxybenzenes. These are organic aromatic compounds containing a monocyclic benzene moiety carrying exactly two methoxy groups.
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Soluble in ethanol (25 mg/mL), DMSO (25 mg/mL), DMF (~10 mg/mL), and 1:2 DMSO:PBS (pH 7.2) (~0.3 mg/mL).
Sensibilidade
Heat sensitive
Índice de refração
n20D1.61
Ponto de fusão (°C)
114-115° C
Peso molecular
266.290 g/mol
XLogP3
2.600
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
4
Exact Mass
266.106 Da
Monoisotopic Mass
266.106 Da
Topological Polar Surface Area
55.100 Ų
Heavy Atom Count
20
Formal Charge
0
Complexity
385.000
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
1
Undefined Bond Stereocenter Count
0
The total count of all stereochemical bonds
1
Covalently-Bonded Unit Count
1
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Revisões
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Perguntas frequentes
What is the purity of this product?
This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 136831-48-6, the molecular formula is C16H14N2O2, and the molecular weight is 266.3 g/mol. InChIKey DBGZNJVTHYFQJI-ZSOIEALJSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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