RO5461111 - ≥98% , CAS No.1252637-46-9

CAS: 1252637-46-9 Cat. No.: R646264 Fórmula: C₂₇H₂₄F₆N₄O₄S Peso molecular: 614.56

GRADE & PURITY ≥98%

Storage

Store at 2-8°C,Protected from light,Desiccated

Shipped In

Wet ice

Visão geral

RO5461111 a highly specific and orally active antagonist of Cathepsin S with IC 50 s of 0.4 nM (human Cathepsin S ) and 0.5 nM (murine Cathepsin S ), respectively. RO5461111 can effectively inhibit the activation of antigen-specific T cells and B cells. RO5461111 can improve pulmonary inflammation and lupus nephritis

Specifications

Especificações e pureza

≥98%

Mecanismos bioquímicos e fisiológicos

RO5461111 a highly specific and orally active antagonist of Cathepsin S with IC 50 s of 0.4 nM (human Cathepsin S ) and 0.5 nM (murine Cathepsin S ), respectively. RO5461111 can effectively inhibit the activation of antigen-specific T cells and B cells. R

Condições de armazenamento de armazenamento

Store at 2-8°C,Protected from light,Desiccated

Enviado em

Wet ice

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Pureza

≥98%

Nomes e identificadores

• Sorrisos canónicos: O=C([C@H]1N(C(C2(C(F)(F)F)CC2)=O)C[C@H](S(=O)(C3=CC=C(C4=CC(C)=NC=C4)C=C3C(F)(F)F)=O)C1)NC5(C#N)CC5
• Peso molecular: 614.56