RP-64477 - ≥98% , CAS No.135239-65-5
Em stock
SKU
R412569
Acyltransferase Inhibitors
Information
RP-64477 RP-64477 is a potent inhibitor of the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) . RP-64477 inhibits ACAT activity with IC50 of 113 nM, 503 nM, and 180 nM in human intestinal (CaCo-2), hepatic (HepG2) and monocytic (THP-1) cell assays, respectively.
Targets
ACAT (CaCo-2 cell-based assay); ACAT (THP-1 cell-based assay); ACAT (HepG2 cell-based assay) 113 nM; 180 nM; 503 nM
Mais informação
| CAS | 135239-65-5 |
|---|---|
| Sinónimos | UNII-K10EML8B3S | Benzamide, n-butyl-3-((4-(decyloxy)benzoyl)amino)-4-(methylthio)- | MS-29261 | N'-Butyl-4-(decyloxy)-4'-(methylthio)-N,3'-bibenzamide | K10EML8B3S | N-butyl-3-(4-(decyloxy)benzamido)-4-(methylthio)benzamide | N-butyl-3-(p-decyloxybenzami |
| Especificações e pureza | ≥98% |
| Condições de armazenamento de armazenamento | Protected from light,Store at -20°C |
| Enviado em | Ice chest + Ice pads |
| Product Description | Information RP-64477 RP-64477 is a potent inhibitor of the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) . RP-64477 inhibits ACAT activity with IC50 of 113 nM, 503 nM, and 180 nM in human intestinal (CaCo-2), hepatic (HepG2) and monocytic (THP-1) cell assays, respectively. Targets ACAT (CaCo-2 cell-based assay); ACAT (THP-1 cell-based assay); ACAT (HepG2 cell-based assay) 113 nM; 180 nM; 503 nM |
| Pubchem Sid | 504765019 |
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504765019 |
| Solubilidade | Solubility (25°C) In vitro DMSO: 100 mg/mL (200.51 mM); Water: Insoluble; Ethanol: Insoluble; |
| Sensibilidade | light sensitive |
| PubChem CID | 9870538 |
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