RSC 133 - Moligand™, ≥98% , CAS No.1418131-46-0

CAS: 1418131-46-0 Cat. No.: R341345 Fórmula: C₁₈H₁₅N₃O₂ Peso molecular: 305.33 Número CE: 808-553-7 PubChem CID: 24799203

GRAU & PUREZA Moligand™, ≥98%

Synonyms

RSC133, >=98% (HPLC) | MS-24410 | EC-000.2551 | SCHEMBL2085437 | AKOS040745336 | 3-[[(E)-3-(1H-indol-3-yl)prop-2-enoyl]amino]benzamide | HYUDSQGICKAEGE-CMDGGOBGSA-N | 1064711-57-4 | rsc133 | RSC-133 | HY-12310 | RSC 133 | 3-[[(2E)-3-(1H-Indol-3-yl)-1-oxo-

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

RSC133 exhibits dual activity by inhibiting histone deacetylase and DNA methyltransferase. RSC133 effectively facilitates reprogramming of human somatic cells to pluripotent stem cells and supports the maintenance of an undifferentiated state of human pluripotent stem cells.

Especificações

Sinónimos

RSC133, >=98% (HPLC) | MS-24410 | EC-000.2551 | SCHEMBL2085437 | AKOS040745336 | 3-[[(E)-3-(1H-indol-3-yl)prop-2-enoyl]amino]benzamide | HYUDSQGICKAEGE-CMDGGOBGSA-N | 1064711-57-4 | rsc133 | RSC-133 | HY-12310 | RSC 133 | 3-[[(2E)-3-(1H-Indol-3-yl)-1-oxo-

Especificações e pureza

Moligand™, ≥98%

Mecanismos bioquímicos e fisiológicos

RSC133 is an epigenetic modulator that effectively enhances reprogramming of human somatic cells and maintenance of human stem cell pluripotency. RSC133 is an epigenetic modulator that effectively enhances reprogramming of human somatic cells and maintena

Condições de armazenamento de armazenamento

Protected from light,Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Grau

Moligand™

Pureza

≥98%

Nomes e identificadores

Pubchem Sid

528766915

Sorrisos canónicos

C1=CC=C2C(=C1)C(=CN2)C=CC(=O)NC3=CC=CC(=C3)C(=O)N

IUPAC Name

3-[[(E)-3-(1H-indol-3-yl)prop-2-enoyl]amino]benzamide

InChIKey

HYUDSQGICKAEGE-CMDGGOBGSA-N

INCHI

1S/C18H15N3O2/c19-18(23)12-4-3-5-14(10-12)21-17(22)9-8-13-11-20-16-7-2-1-6-15(13)16/h1-11,20H,(H2,19,23)(H,21,22)/b9-8+

SMILES isoméricas

C1=CC=C2C(=C1)C(=CN2)/C=C/C(=O)NC3=CC=CC(=C3)C(=O)N

WGK Alemanha

3

PubChem CID

24799203

Peso molecular

305.33

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Benzoic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Benzoic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Acylaminobenzoic acid and derivatives
• Alternative Parents: Indoles Benzamides Anilides N-arylamides Benzoyl derivatives Substituted pyrroles Heteroaromatic compounds Secondary carboxylic acid amides Primary carboxylic acid amides Azacyclic compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Acylaminobenzoic acid or derivatives - Benzamide - Indole - Indole or derivatives - Anilide - Benzoyl - N-arylamide - Substituted pyrrole - Pyrrole - Heteroaromatic compound - Secondary carboxylic acid amide - Primary carboxylic acid amide - Carboxamide group - Carboxylic acid derivative - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Carbonyl group - Organic oxygen compound - Aromatic heteropolycyclic compound
• Descrição: This compound belongs to the class of organic compounds known as acylaminobenzoic acid and derivatives. These are derivatives of amino benzoic acid derivatives where the amine group is N-acylated.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriedades químicas e físicas

• Sensibilidade: light sensitive
• Peso molecular: 305.300 g/mol
• XLogP3: 2.200
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 305.116 Da
• Monoisotopic Mass: 305.116 Da
• Topological Polar Surface Area: 88.000 Ų
• Heavy Atom Count: 23
• Formal Charge: 0
• Complexity: 477.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 1
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 1