SGC3027 - ≥98% , CAS No.2624313-13-7

CAS: 2624313-13-7 Cat. No.: S651967 Fórmula: C₄₁H₄₇ClN₆O₆S Peso molecular: 787.37

GRADE & PURITY ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

SGC3027 is a histone methyltransferase inhibitor SGC3027 is the first potent, selective and cell active chemical probe for PRMT7 .

In Vitro

SGC3027 is a pro-drug of SGC8158 which releases the active component upon reduction in the cell by reductases.? In cellular assays using C2C12 cells, SGC3027 inhibits the methylation of HSP70 with IC 50 =1.3 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:PRMT7

Specifications

Especificações e pureza

≥98%

Mecanismos bioquímicos e fisiológicos

SGC3027 is a histone methyltransferase inhibitor. SGC3027 is the first potent, selective and cell active chemical probe for PRMT7.

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Pureza

≥98%

Nomes e identificadores

• Sorrisos canónicos: ClC1=CC=C(C2=CC(CN(C(CC(C)(C)C3=C(C)C(C(C)=C(C)C3=O)=O)=O)CCCCSC[C@@H]4[C@@H](O)[C@@H](O)[C@H](N5C(N=CN=C6N)=C6N=C5)O4)=CC=C2)C=C1
• Peso molecular: 787.37

Propriedades químicas e físicas

• Solubilidade: DMSO : 250 mg/mL (317.51 mM; Need ultrasonic)