Sivelestat sodium - Moligand™, 10 mM in DMSO , CAS No.150374-95-1

CAS: 150374-95-1 Cat. No.: S1498686 Fórmula: C₂₀H₂₁N₂NaO₇S Peso molecular: 456.44 PubChem CID: 23664980

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral

Sivelestat (EI546) sodium is a competitive inhibitor of human neutrophil elastase , with an IC 50 of 44 nM and a K i of 200 nM. Sivelestat (EI546) sodium has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19 .

Specifications

Especificações e pureza

Moligand™, 10 mM in DMSO

Condições de armazenamento de armazenamento

Desiccated,Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Grau

Moligand™

Nomes e identificadores

• SMILES isoméricas: CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)[O-].[Na+]
• PubChem CID: 23664980
• Peso molecular: 456.44

Referências

1. Hao-Dong Yang, Zhi-Shu Tang, Tao-Tao Xue, Huai-Li Xu, Bao-Long Hou, Ya-Ya Zhu, Zeng-Hu Su, Hong-Bo Xu.  (2023)  Monoterpenoids from the root bark of Acanthopanax gracilistylus and their inhibitory effects on neutrophil elastase, 5-lipoxygenase, andcyclooxygenase-2 in vitro.  PHYTOCHEMISTRY,      [PMID:37683990] [10.1016/j.phytochem.2023.113851]

2. Hao-Dong Yang, Yuan-Gui Yang, Zhi-Shu Tang, Kang Ma, Hong-Bo Xu.  (2024)  Identification of lignans as selective cyclooxygenase-2 inhibitors from the extract of Acanthopanacis cortex.  PHYTOCHEMISTRY,      [PMID:38972441] [10.1016/j.phytochem.2024.114208]