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SJFα - ≥99% , CAS No.2254609-27-1
Disponível para encomenda
GRADE & PURITY ≥99%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Application
PROTAC
224,000+ produtos de pesquisa · Triple ISO certified · COA & SDS Disponível para todos os produtos · Envio no mesmo dia em itens em estoque
Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Visão geral
SJFα is a 13-atom linker PROTAC based on von Hippel-Lindau ligand. SJFα degrades p38α with a DC 50 of 7.16 nM, but is far less effective at degrading p38δ (DC 50 =299 nM) and does not degrade the other p38 isoforms (β and γ) at concentrations up to 2.5 µM
Form:Solid
IC50& Target:p38α 7.16 nM (DC 50 ) p38δ 299 nM (DC 50 ) VHL
Specifications
Especificações e pureza
≥99%
Mecanismos bioquímicos e fisiológicos
SJFα is a 13-atom linker PROTAC based on von Hippel-Lindau ligand. SJFα degrades p38α with a DC 50 of 7.16u2009u2009nM, but is far less effective at degrading p38δ (DC 50 =299u2009nM) and does not degrade the other p38 isoforms (β and γ) at concentrations
Condições de armazenamento de armazenamento
Store at -20°C
Enviado em
Ice chest + Ice pads
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Pureza
≥99%
Nomes e identificadores
| Peso molecular | 1120.27 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificados（CoA,COO,BSE/TSE e Mapa de Análise)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propriedades químicas e físicas
| Solubilidade | DMSO : 100 mg/mL (89.26 mM; ultrasonic and warming and heat to 60°C) |
|---|
Calculadoras de soluções
Revisões
Avaliações dos Clientes
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