SU5204 - ≥98%, EZ tautomeric mixture , CAS No.186611-11-0

CAS: 186611-11-0 Cat. No.: S412303 Fórmula: C₁₇H₁₅NO₂ Peso molecular: 265.31 PubChem CID: 6509031

GRADE & PURITY ≥98%, EZ tautomeric mixture

Synonyms

2H-​Indol-​2-​one,3-​[(2-​ethoxyphenyl)​methylene]​-​1,​3-​dihydro-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

Information

SU5204 is a tyrosine kinase inhibitor with IC50 of 4 μM and 51.5 μM forFLK-1 (VEGFR-2)andHER2, respectively.

Targets

VEGFR-2 (Cell-free assay); HER2 (Cell-free assay) 4 μM; 51.5 μM

Specifications

Sinónimos

2H-​Indol-​2-​one,3-​[(2-​ethoxyphenyl)​methylene]​-​1,​3-​dihydro-

Especificações e pureza

≥98%, EZ tautomeric mixture

Mecanismos bioquímicos e fisiológicos

SU5204 is a tyrosine kinase inhibitor with IC50 of 4 μM and 51.5 μM for FLK-1 (VEGFR-2) and HER2, respectively.

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Pureza

≥98%

Propriedades do produto

• ALogP: 3.063
• Contagem HBD: 1
• Ligação rotativa: 3

Nomes e identificadores

• Pubchem Sid: 504764270
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504764270
• Sorrisos canónicos: CCOC1=CC=CC=C1C=C2C3=CC=CC=C3NC2=O
• IUPAC Name: (3Z)-3-[(2-ethoxyphenyl)methylidene]-1H-indol-2-one
• InChIKey: MEZFKCPUSMBMAY-KAMYIIQDSA-N
• INCHI: 1S/C17H15NO2/c1-2-20-16-10-6-3-7-12(16)11-14-13-8-4-5-9-15(13)18-17(14)19/h3-11H,2H2,1H3,(H,18,19)/b14-11-
• PubChem CID: 6509031
• Peso molecular: 265.31

Propriedades químicas e físicas

• Solubilidade: Solubility (25°C) In vitro DMSO: 53 mg/mL (199.76 mM); Water: Insoluble; Ethanol: Insoluble
• DMSO (mg/mL) Solubilidade máxima: 53
• DMSO (mM) Solubilidade máxima: 199.766311107761
• Água (mg/mL) Solubilidade máxima: ＜1

Perguntas frequentes

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 186611-11-0, the molecular formula is C17H15NO2, and the molecular weight is 265.31 g/mol. InChIKey MEZFKCPUSMBMAY-KAMYIIQDSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.