≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
SU5205 is an inhibitor ofVEGF receptor 2 (VEGFR2/FLK-1)with IC50 of 9.6 µM.
Targets
VEGFR2 (Cell-free assay) 9.6 μM
| ALogP | 2.936 |
|---|---|
| Contagem HBD | 1 |
| Ligação rotativa | 1 |
| Pubchem Sid | 504763820 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504763820 |
| Sorrisos canónicos | C1=CC=C2C(=C1)C(=CC3=CC=C(C=C3)F)C(=O)N2 |
| IUPAC Name | (3Z)-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one |
| InChIKey | QIERHADIMMFZNE-LCYFTJDESA-N |
| INCHI | 1S/C15H10FNO/c16-11-7-5-10(6-8-11)9-13-12-3-1-2-4-14(12)17-15(13)18/h1-9H,(H,17,18)/b13-9- |
| SMILES isoméricas | C1=CC=C2C(=C1)/C(=C/C3=CC=C(C=C3)F)/C(=O)N2 |
| PubChem CID | 5398217 |
| Peso molecular | 239.24 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Classe | Indoles and derivatives |
| Subclass | Indolines |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Indolines |
| Alternative Parents | Fluorobenzenes Aryl fluorides Secondary carboxylic acid amides Lactams Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organofluorides Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Dihydroindole - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - Monocyclic benzene moiety - Benzenoid - Carboxamide group - Lactam - Secondary carboxylic acid amide - Azacycle - Carboxylic acid derivative - Organofluoride - Organohalogen compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Carbonyl group - Organopnictogen compound - Organonitrogen compound - Organooxygen compound - Organic oxygen compound - Aromatic heteropolycyclic compound |
| Descrição | This compound belongs to the class of organic compounds known as indolines. These are compounds containing an indole moiety, which consists of pyrrolidine ring fused to benzene to form 2,3-dihydroindole. |
| External Descriptors | Not available |
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Data | Item |
|---|---|---|---|
 C2301107 | Certificate of Analysis | Dec 12, 2025 | S413644 |
| C2301108 | Certificate of Analysis | Dec 12, 2025 | S413644 |
| C2301109 | Certificate of Analysis | Dec 12, 2025 | S413644 |
| C2301111 | Certificate of Analysis | Dec 12, 2025 | S413644 |
| Solubilidade | Solubility (25°C) In vitro DMSO: 48 mg/mL (200.63 mM); Ethanol: 3 mg/mL (12.53 mM); Water: Insoluble; |
|---|---|
| DMSO (mg/mL) Solubilidade máxima | 48 |
| DMSO (mM) Solubilidade máxima | 200.63534525999 |
| Água (mg/mL) Solubilidade máxima | ＜1 |
| Peso molecular | 239.240 g/mol |
| XLogP3 | 3.000 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 1 |
| Exact Mass | 239.075 Da |
| Monoisotopic Mass | 239.075 Da |
| Topological Polar Surface Area | 29.100 Ų |
| Heavy Atom Count | 18 |
| Formal Charge | 0 |
| Complexity | 358.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 1 |
| Covalently-Bonded Unit Count | 1 |
