≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Visão geral
TA-3166 (Megakaryocytes/platelets inducing agent) is a novel chemically synthesized c-MPL agonist (CMA) and thrombopoietin (TPO) receptor agonist. TA-316 enhances ex vivo platelet generation from human-induced pluripotent stem (iPS) cells.
In Vitro
TA-316 (0.01-1000 nM; 4 days) stimulates UT-7/TPO and Ba/F3-HuMpl cells proliferation, with the EC 50 values of 0.3 and 0.65 nM, respectively. ?\nTA-316 (800 nM; 10 days) promotes biased megakaryopoiesis and upregulated MK lineage markers. ?\nTA-316 (200 nM; 4 days) preferentially enhances VEGFA and FGF2 expression. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: UT-7/TPO and Ba/F3-HuMpl cells Concentration: 0.01-1000 nM Incubation Time: 4 days Result: Stimulated UT-7/TPO and Ba/F3-HuMpl cell proliferation.
Form:Solid
Specifications
Especificações e pureza
≥98%
Mecanismos bioquímicos e fisiológicos
TA-3166 (Megakaryocytes/platelets inducing agent) is a novel chemically synthesized c-MPL agonist (CMA) and thrombopoietin (TPO) receptor agonist. TA-316 enhances ex vivo platelet generation from human-induced pluripotent stem (iPS) cells.
Condições de armazenamento de armazenamento
Store at -20°C
Enviado em
Ice chest + Ice pads
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
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