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MAP3K1

DescriçãoMitogen-activated protein kinase kinase kinase 1

Gene and Protein Information

Gene ID4214
Uniprot Accession IDs Q13233
Ensembl ID ENSP00000382423
Symbol MAPKKK1 MEKK MEKK1 MEKK MEKK1 SRXY6 MEKK 1 MAPKKK1
FamilyBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Sequence
MAAAAGNRASSSGFPGARATSPEAGGGGGALKASSAPAAAAGLLREAGSGGRERADWRRRQLRKVRSVELDQLPEQPLFLAASPPASSTSPSPEPADAAGSGTGFQPVAVPPPHGAASRGGAHLTESVAAPDSGASSPAAAEPGEKRAPAAEPSPAAAPAGREMENKETLKGLHKMDDRPEERMIREKLKATCMPAWKHEWLERRNRRGPVVVKPIPVKGDGSEMNHLAAESPGEVQASAASPASKGRRSPSPGNSPSGRTVKSESPGVRRKRVSPVPFQSGRITPPRRAPSPDGFSPYSPEETNRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKYRVFIGPQNCSCARGTFCIHLLFVMLRVFQLEPSDPMLWRKTLKNFEVESLFQKYHSRRSSRIKAPSRNTIQKFVSRMSNSHTLSSSSTSTSSSENSIKDEEEQMCPICLLGMLDEESLTVCEDGCRNKLHHHCMSIWAEECRRNREPLICPLCRSKWRSHDFYSHELSSPVDSPSSLRAAQQQTVQQQPLAGSRRNQESNFNLTHYGTQQIPPAYKDLAEPWIQVFGMELVGCLFSRNWNVREMALRRLSHDVSGALLLANGESTGNSGGSSGSSPSGGATSGSSQTSISGDVVEACCSVLSMVCADPVYKVYVAALKTLRAMLVYTPCHSLAERIKLQRLLQPVVDTILVKCADANSRTSQLSISTLLELCKGQAGELAVGREILKAGSIGIGGVDYVLNCILGNQTESNNWQELLGRLCLIDRLLLEFPAEFYPHIVSTDVSQAEPVEIRYKKLLSLLTFALQSIDNSHSMVGKLSRRIYLSSARMVTTVPHVFSKLLEMLSVSSSTHFTRMRRRLMAIADEVEIAEAIQLGVEDTLDGQQDSFLQASVPNNYLETTENSSPECTVHLEKTGKGLCATKLSASSEDISERLASISVGPSSSTTTTTTTTEQPKPMVQTKGRPHSQCLNSSPLSHHSQLMFPALSTPSSSTPSVPAGTATDVSKHRLQGFIPCRIPSASPQTQRKFSLQFHRNCPENKDSDKLSPVFTQSRPLPSSNIHRPKPSRPTPGNTSKQGDPSKNSMTLDLNSSSKCDDSFGCSSNSSNAVIPSDETVFTPVEEKCRLDVNTELNSSIEDLLEASMPSSDTTVTFKSEVAVLSPEKAENDDTYKDDVNHNQKCKEKMEAEEEEALAIAMAMSASQDALPIVPQLQVENGEDIIIIQQDTPETLPGHTKAKQPYREDTEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLKHPVFRTTW
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNomeNúmero de identificação fiscalOther Gene IDSources
Chimp471543MAP3K1mitogen-activated protein kinase kinase kinase 19598VGNC:8626OMA, EggNOG
Macaque710979MAP3K1mitogen-activated protein kinase kinase kinase 19544Inparanoid, OMA
Mouse26401Map3k1mitogen-activated protein kinase kinase kinase 110090MGI:1346872Inparanoid, OMA, EggNOG
Rat116667Map3k1mitogen-activated protein kinase kinase kinase 110116RGD:620966Inparanoid, OMA, EggNOG
Dog478061MAP3K1mitogen-activated protein kinase kinase kinase 19615VGNC:42966Inparanoid, OMA, EggNOG
Horse100061688MAP3K1mitogen-activated protein kinase kinase kinase 19796VGNC:19930Inparanoid, OMA, EggNOG
Cow523962MAP3K1mitogen-activated protein kinase kinase kinase 19913VGNC:31188Inparanoid, OMA, EggNOG
Pig396617MAP3K1mitogen-activated protein kinase kinase kinase 19823Inparanoid, OMA, EggNOG
Opossum100032065MAP3K1mitogen-activated protein kinase kinase kinase 113616Inparanoid, OMA, EggNOG
Platypus100076612MAP3K1mitogen-activated protein kinase kinase kinase 19258Inparanoid, OMA, EggNOG
Chicken427144MAP3K1mitogen-activated protein kinase kinase kinase 19031CGNC:10913Inparanoid, OMA, EggNOG
Anole lizard100561745map3k1mitogen-activated protein kinase kinase kinase 128377Inparanoid, OMA, EggNOG
Xenopusmap3k1mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase [Source:Xenbase;Acc:XB-GENE-1008434]8364OMA, EggNOG
Zebrafish100334486map3k1mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase7955ZDB-GENE-090313-412Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    STE group    /    STE11 family    /    Mitogen-activated protein kinase kinase kinase 1

Associated Recombinant Proteins

NomeSpecification and purityExpression systemProtein labelDisponibilidadeVer Detalhes

Associated Antibodies

NomeSpecificationsSpecies reactivityAplicaçãoDisponibilidadeVer Detalhes

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NomeDirect Associated TargetsDisease TypeMondoid

      Bibliography

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