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MAP4K1

DescriçãoMitogen-activated protein kinase kinase kinase kinase 1

Gene and Protein Information

Gene ID11184
Uniprot Accession IDs Q92918
Ensembl ID ENSP00000465039
Symbol HPK1 HPK1
FamilyBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Sequence
MDVVDPDIFNRDPRDHYDLLQRLGGGTYGEVFKARDKVSGDLVALKMVKMEPDDDVSTLQKEILILKTCRHANIVAYHGSYLWLQKLWICMEFCGAGSLQDIYQVTGSLSELQISYVCREVLQGLAYLHSQKKIHRDIKGANILINDAGEVRLADFGISAQIGATLARRLSFIGTPYWMAPEVAAVALKGGYNELCDIWSLGITAIELAELQPPLFDVHPLRVLFLMTKSGYQPPRLKEKGKWSAAFHNFIKVTLTKSPKKRPSATKMLSHQLVSQPGLNRGLILDLLDKLKNPGKGPSIGDIEDEEPELPPAIPRRIRSTHRSSSLGIPDADCCRRHMEFRKLRGMETRPPANTARLQPPRDLRSSSPRKQLSESSDDDYDDVDIPTPAEDTPPPLPPKPKFRSPSDEGPGSMGDDGQLSPGVLVRCASGPPPNSPRPGPPPSTSSPHLTAHSEPSLWNPPSRELDKPPLLPPKKEKMKRKGCALLVKLFNGCPLRIHSTAAWTHPSTKDQHLLLGAEEGIFILNRNDQEATLEMLFPSRTTWVYSINNVLMSLSGKTPHLYSHSILGLLERKETRAGNPIAHISPHRLLARKNMVSTKIQDTKGCRACCVAEGASSGGPFLCGALETSVVLLQWYQPMNKFLLVRQVLFPLPTPLSVFALLTGPGSELPAVCIGVSPGRPGKSVLFHTVRFGALSCWLGEMSTEHRGPVQVTQVEEDMVMVLMDGSVKLVTPEGSPVRGLRTPEIPMTEAVEAVAMVGGQLQAFWKHGVQVWALGSDQLLQELRDPTLTFRLLGSPRLECSGTISPHCNLLLPGSSNSPASASRVAGITGL
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNomeNúmero de identificação fiscalOther Gene IDSources
Chimp748652MAP4K1mitogen-activated protein kinase kinase kinase kinase 19598VGNC:7488OMA, EggNOG
Mouse26411Map4k1mitogen-activated protein kinase kinase kinase kinase 110090MGI:1346882Inparanoid, OMA, EggNOG
Rat292763Map4k1mitogen activated protein kinase kinase kinase kinase 110116RGD:1305463Inparanoid, OMA, EggNOG
Dog484527MAP4K1mitogen-activated protein kinase kinase kinase kinase 19615VGNC:42981Inparanoid, OMA, EggNOG
Horse100064279MAP4K1mitogen-activated protein kinase kinase kinase kinase 19796VGNC:19945Inparanoid, OMA, EggNOG
Cow522002MAP4K1mitogen-activated protein kinase kinase kinase kinase 19913VGNC:31204Inparanoid, OMA, EggNOG
Pig100516374MAP4K1mitogen-activated protein kinase kinase kinase kinase 19823OMA, EggNOG
Opossum100013272MAP4K1mitogen-activated protein kinase kinase kinase kinase 113616Inparanoid, OMA, EggNOG
Anole lizard100558628map4k1mitogen-activated protein kinase kinase kinase kinase 128377Inparanoid, OMA, EggNOG
Xenopus100216063map4k5mitogen-activated protein kinase kinase kinase kinase 58364XB-GENE-6037447OMA, EggNOG

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    STE group    /    STE20 family    /    KHS subfamily    /    Mitogen-activated protein kinase kinase kinase kinase 1

Associated Recombinant Proteins

NomeSpecification and purityExpression systemProtein labelDisponibilidadeVer Detalhes

Associated Antibodies

NomeSpecificationsSpecies reactivityAplicaçãoDisponibilidadeVer Detalhes

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NomeDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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