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ABL1

DescriçãoTyrosine-protein kinase ABL1

Gene and Protein Information

Gene ID25
Uniprot Accession IDs P00519 A3KFJ3 Q13869 Q13870 Q16133 Q17R61 Q45F09
Ensembl ID ENSP00000361423
Symbol ABL JTK7 ABL JTK7 p150 c-ABL v-abl CHDSKM c-ABL1 bcr/abl
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family. ABL subfamily.
Sequence
MLEICLKLVGCKSKKGLSSSSSCYLEEALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLATGEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSSTAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATAGSGPAATQDFSKLLSSVKEISDIVQR
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNomeNúmero de identificação fiscalOther Gene IDSources
Chimp107976801ABL1ABL proto-oncogene 1, non-receptor tyrosine kinase9598VGNC:4596OMA, EggNOG
Macaque722449ABL1ABL proto-oncogene 1, non-receptor tyrosine kinase9544Inparanoid, OMA, EggNOG
Mouse11350Abl1c-abl oncogene 1, non-receptor tyrosine kinase10090MGI:87859Inparanoid, OMA, EggNOG
Rat311860Abl1ABL proto-oncogene 1, non-receptor tyrosine kinase10116RGD:1584969Inparanoid, OMA, EggNOG
Dog491292ABL1ABL proto-oncogene 1, non-receptor tyrosine kinase9615Inparanoid, OMA, EggNOG
Horse100069715ABL1ABL proto-oncogene 1, non-receptor tyrosine kinase9796VGNC:49495Inparanoid, OMA, EggNOG
Cow540876ABL1ABL proto-oncogene 1, non-receptor tyrosine kinase9913VGNC:50224Inparanoid, OMA, EggNOG
Pig100524544ABL1ABL proto-oncogene 1, non-receptor tyrosine kinase9823Inparanoid, OMA, EggNOG
OpossumABL1ABL proto-oncogene 1, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:76]13616Inparanoid, EggNOG
Platypus100075676ABL1ABL proto-oncogene 1, non-receptor tyrosine kinase9258Inparanoid, OMA, EggNOG
Chicken417181ABL1ABL proto-oncogene 1, non-receptor tyrosine kinase9031CGNC:2837Inparanoid, OMA, EggNOG
Anole lizard100557530abl1ABL proto-oncogene 1, non-receptor tyrosine kinase28377Inparanoid, OMA
Xenopusabl1ABL proto-oncogene 1, non-receptor tyrosine kinase [Source:Xenbase;Acc:XB-GENE-6054675]8364OMA, EggNOG
Zebrafish100000720abl1c-abl oncogene 1, non-receptor tyrosine kinase7955ZDB-GENE-100812-9Inparanoid, OMA
Fruitfly45821AblAbl tyrosine kinase7227FBgn0000017Inparanoid, EggNOG

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    ABL family    /    Tyrosine-protein kinase abl1

Associated Recombinant Proteins

NomeSpecification and purityExpression systemProtein labelDisponibilidadeVer Detalhes

Associated Antibodies

NomeEspecificaçõesSpecies reactivityAplicaçãoDisponibilidadeVer Detalhes

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NomeDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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