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KIT

DescriçãoMast/stem cell growth factor receptor Kit

Gene and Protein Information

Gene ID3815
Uniprot Accession IDs P10721 B5A956 D5LXN2 D5M931 F5H8F8 Q6IQ28 Q99662 Q9UM99 SCFR
Ensembl ID ENSP00000288135
Symbol SCFR PBT SCFR C-Kit CD117 MASTC
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Sequence
MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTDPGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLVDRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWEDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDVGKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCIIVMILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSCSDSTNEYMDMKPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSVGSTASSSQPLLVHDDV
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNomeNúmero de identificação fiscalOther Gene IDSources
Chimp461316KITKIT proto-oncogene receptor tyrosine kinase9598VGNC:6662OMA, EggNOG
Mouse16590KitKIT proto-oncogene receptor tyrosine kinase10090MGI:96677Inparanoid, OMA, EggNOG
Rat64030KitKIT proto-oncogene receptor tyrosine kinase10116RGD:620568Inparanoid, OMA, EggNOG
Dog403811KITKIT proto-oncogene receptor tyrosine kinase9615VGNC:42422Inparanoid, OMA, EggNOG
Horse100009704KITKIT proto-oncogene receptor tyrosine kinase9796VGNC:19433Inparanoid, OMA, EggNOG
Cow280832KITKIT proto-oncogene receptor tyrosine kinase9913VGNC:30618Inparanoid, OMA, EggNOG
Pig396810KITKIT proto-oncogene receptor tyrosine kinase9823Inparanoid, OMA, EggNOG
Opossum100017501KITKIT proto-oncogene receptor tyrosine kinase13616Inparanoid, OMA, EggNOG
Platypus100075317KITKIT proto-oncogene receptor tyrosine kinase9258Inparanoid, OMA, EggNOG
Anole lizard100551543kitKIT proto-oncogene receptor tyrosine kinase28377Inparanoid, OMA, EggNOG
XenopusKITKIT proto-oncogene receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6342]8364OMA, EggNOG
Zebrafish30256kitav-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a7955ZDB-GENE-980526-464OMA, EggNOG
Zebrafish497629kitbv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b7955ZDB-GENE-050916-2Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    PDGFR family    /    Mast/stem cell growth factor receptor kit

Associated Recombinant Proteins

NomeSpecification and purityExpression systemProtein labelDisponibilidadeVer Detalhes

Associated Antibodies

NomeSpecificationsSpecies reactivityAplicaçãoDisponibilidadeVer Detalhes

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NomeDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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