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ROCK1

DescriçãoRho-associated protein kinase 1

Gene and Protein Information

Gene ID6093
Uniprot Accession IDs Q13464 B0YJ91 Q2KHM4 Q59GZ4
Ensembl ID ENSP00000382697
Symbol ROCK-I P160ROCK
FamilyBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
Sequence
MSTGDSFETRFEKMDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGEEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQMQLASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSVPNRGNIKRYGWKKQYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILYANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCDACAKPLWHVFKPPPALECRRCHVKCHRDHLDKKEDLICPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNPPSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNomeNúmero de identificação fiscalOther Gene IDSources
Chimp455326ROCK1Rho associated coiled-coil containing protein kinase 19598VGNC:7330OMA, EggNOG
Macaque698223ROCK1Rho associated coiled-coil containing protein kinase 19544Inparanoid, OMA, EggNOG
Mouse19877Rock1Rho-associated coiled-coil containing protein kinase 110090MGI:107927Inparanoid, OMA, EggNOG
Rat81762Rock1Rho-associated coiled-coil containing protein kinase 110116RGD:620424Inparanoid, OMA, EggNOG
Dog480181ROCK1Rho associated coiled-coil containing protein kinase 19615VGNC:45688Inparanoid, OMA, EggNOG
Horse100034056ROCK1Rho associated coiled-coil containing protein kinase 19796VGNC:22496Inparanoid, OMA, EggNOG
Cow785911ROCK1Rho associated coiled-coil containing protein kinase 19913OMA, EggNOG
Pig397447ROCK1Rho associated coiled-coil containing protein kinase 19823Inparanoid, OMA, EggNOG
Opossum100618269ROCK1Rho associated coiled-coil containing protein kinase 113616Inparanoid, OMA
Chicken373970ROCK1Rho-associated, coiled-coil containing protein kinase 19031CGNC:11078Inparanoid, OMA
Anole lizard100558337rock1Rho associated coiled-coil containing protein kinase 128377Inparanoid, OMA
Zebrafish100329779rock1Rho-associated, coiled-coil containing protein kinase 17955ZDB-GENE-100712-2Inparanoid, OMA

Associated Recombinant Proteins

NomeSpecification and purityExpression systemProtein labelDisponibilidadeVer Detalhes

Associated Antibodies

NomeSpecificationsSpecies reactivityAplicaçãoDisponibilidadeVer Detalhes

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NomeDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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