tCFA15 - ≥99% , CAS No.220757-88-0

CAS: 220757-88-0 Cat. No.: T649810 Fórmula: C₂₄H₄₄O₂ Peso molecular: 364.6 PubChem CID: 9799188

GRADE & PURITY ≥99%

Synonyms

tCFA15 | 2-Cyclohexen-1-one, 3-(15-hydroxypentadecyl)-2,4,4-trimethyl- | SCHEMBL580196 | 3-(15-HYDROXYPENTADECYL)-2,4,4-TRIMETHYLCYCLOHEX-2-EN-1-ONE | DTXSID30430917 | HY-104031 | VIA75788 | 3-(15-hydroxypentadecyl)-2,4,4-trimethyl-2-cyclohexen-1-one | 2,

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

tCFA15 is a trimethyl cyclohexenonic long chain fatty alcohol containing 15 carbon atoms on the side chain, promotes the differentiation of neurons, and may regulates Notch signaling.

In Vitro

tCFA15 (10 nM-1 μM) dose-dependently affects the differentiation of neural stem cell-derived neurospheres by promoting neurons at the expense of astrocytes, and such effect is via Notch1. tCFA15 (1 μM) specifically decreases the level of Notch1 mRNA in spheres, and such an effect is also observed in decreases Notch1 expression in neuronal and glial cell cultures. tCFA15 stimulates arginine Vasotocin secretion in nerve terminals of the neurohypophysis. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Oil

IC50& Target:Notch1

Specifications

Sinónimos

tCFA15 | 2-Cyclohexen-1-one, 3-(15-hydroxypentadecyl)-2,4,4-trimethyl- | SCHEMBL580196 | 3-(15-HYDROXYPENTADECYL)-2,4,4-TRIMETHYLCYCLOHEX-2-EN-1-ONE | DTXSID30430917 | HY-104031 | VIA75788 | 3-(15-hydroxypentadecyl)-2,4,4-trimethyl-2-cyclohexen-1-one | 2,

Especificações e pureza

≥99%

Mecanismos bioquímicos e fisiológicos

tCFA15 is a trimethyl cyclohexenonic long chain fatty alcohol containing 15 carbon atoms on the side chain, promotes the differentiation of neurons, and may regulates Notch signaling.

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Pureza

≥99%

Nomes e identificadores

• Sorrisos canónicos: CC1=C(C(CCC1=O)(C)C)CCCCCCCCCCCCCCCO
• IUPAC Name: 3-(15-hydroxypentadecyl)-2,4,4-trimethylcyclohex-2-en-1-one
• InChIKey: FGMAOXGOTRUOKJ-UHFFFAOYSA-N
• INCHI: 1S/C24H44O2/c1-21-22(24(2,3)19-18-23(21)26)17-15-13-11-9-7-5-4-6-8-10-12-14-16-20-25/h25H,4-20H2,1-3H3
• SMILES isoméricas: CC1=C(C(CCC1=O)(C)C)CCCCCCCCCCCCCCCO
• PubChem CID: 9799188
• Peso molecular: 364.6

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Classe Fatty Acyls
      • Subclass Fatty alcohols

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Classe: Fatty Acyls
• Subclass: Fatty alcohols
• Intermediate Tree Nodes: Not available
• Direct Parent: Long-chain fatty alcohols
• Alternative Parents: Cyclohexenones Primary alcohols Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic homomonocyclic compounds
• Substituents: Long chain fatty alcohol - Cyclohexenone - Cyclic ketone - Ketone - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Primary alcohol - Organooxygen compound - Carbonyl group - Alcohol - Aliphatic homomonocyclic compound
• Descrição: This compound belongs to the class of organic compounds known as long-chain fatty alcohols. These are fatty alcohols that have an aliphatic tail of 13 to 21 carbon atoms.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mecanismos de ação

Propriedades químicas e físicas

• Solubilidade: DMSO : 130 mg/mL (356.56 mM; Need ultrasonic)
• Peso molecular: 364.600 g/mol
• XLogP3: 7.900
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 15
• Exact Mass: 364.334 Da
• Monoisotopic Mass: 364.334 Da
• Topological Polar Surface Area: 37.300 Ų
• Heavy Atom Count: 26
• Formal Charge: 0
• Complexity: 420.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Perguntas frequentes

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 220757-88-0, the molecular formula is C24H44O2, and the molecular weight is 364.6 g/mol. InChIKey FGMAOXGOTRUOKJ-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.