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· · COA & SDS Disponível para todos os produtos · Envio no mesmo dia em itens em estoque Tenidap - Moligand™, ≥98% , Activator of K ir2.3, CAS No.120210-48-2, Activator of K ir2.3
Disponível para encomenda
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% Synonyms
BDBM50331888 | 5-chloro-2-hydroxy-3-(thiophene-2-carbonyl)indole-1-carboxamide | (Z)-5-chloro-3-(hydroxy(thiophen-2-yl)methylene)-2-oxoindoline-1-carboxamide | CP-66248 | VEA21048 | NCGC00160352-01 | Tenidapum [INN-Latin] | NCGC00263542-01 | (3Z)-5-Chloro
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Why this grade Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Visão geral Tenidap (CP-66248) is a selective COX-1 and SLC26A3 inhibitor with anti-inflammatory, analgesic, and anti-rheumatic activities.
Specifications Sinónimos
BDBM50331888 | 5-chloro-2-hydroxy-3-(thiophene-2-carbonyl)indole-1-carboxamide | (Z)-5-chloro-3-(hydroxy(thiophen-2-yl)methylene)-2-oxoindoline-1-carboxamide | CP-66248 | VEA21048 | NCGC00160352-01 | Tenidapum [INN-Latin] | NCGC00263542-01 | (3Z)-5-Chloro
Especificações e pureza
Moligand™, ≥98%
Mecanismos bioquímicos e fisiológicos
NSAID that preferentially inhibits COX-1 (IC50values are < 0.03, 1.2 and > 30μM for COX-1, COX-2 and 5-lipoxygenase respectively). Inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocyte
Condições de armazenamento de armazenamento
Store at 2-8°C
Enviado em
Wet ice
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Mecanismo de ação
Activator of K ir2.3
Nomes e identificadores Sorrisos canónicos C1=CSC(=C1)C(=O)C2=C(N(C3=C2C=C(C=C3)Cl)C(=O)N)O IUPAC Name 5-chloro-2-hydroxy-3-(thiophene-2-carbonyl)indole-1-carboxamide InChIKey IZSFDUMVCVVWKW-UHFFFAOYSA-N INCHI 1S/C14H9ClN2O3S/c15-7-3-4-9-8(6-7)11(13(19)17(9)14(16)20)12(18)10-2-1-5-21-10/h1-6,19H,(H2,16,20) SMILES isoméricas C1=CSC(=C1)C(=O)C2=C(N(C3=C2C=C(C=C3)Cl)C(=O)N)O WGK Alemanha 3 PubChem CID 60712 Peso molecular 320.75
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Classe Indoles and derivatives Subclass Indolecarboxylic acids and derivatives Intermediate Tree Nodes Not available Direct Parent Indolecarboxamides and derivatives Alternative Parents Hydroxyindoles Indoles Aryl ketones Thiophene carboxylic acids and derivatives Pyrrole carboxamides Aryl chlorides Benzenoids Substituted pyrroles Vinylogous amides Vinylogous acids Heteroaromatic compounds Ureas Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives Organonitrogen compounds Organic oxides Organochlorides Molecular Framework Aromatic heteropolycyclic compounds Substituents Indolecarboxamide derivative - Hydroxyindole - Indole - Pyrrole-1-carboxamide - Pyrrole-1-carboxylic acid or derivatives - Thiophene carboxylic acid or derivatives - Aryl ketone - Aryl chloride - Aryl halide - Substituted pyrrole - Benzenoid - Heteroaromatic compound - Pyrrole - Vinylogous amide - Vinylogous acid - Thiophene - Carbonic acid derivative - Urea - Ketone - Azacycle - Organonitrogen compound - Organochloride - Organohalogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound Descrição This compound belongs to the class of organic compounds known as indolecarboxamides and derivatives. These are compounds containing a carboxamide group attached to an indole. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estrutura 3D Alvos associados (humanos) Certificados（CoA,COO,BSE/TSE e Mapa de Análise) Propriedades químicas e físicas Solubilidade Solvent:DMSO, Max Conc. mg/mL: 32.07, Max Conc. mM: 100 Peso molecular 320.800 g/mol XLogP3 3.800 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 4 Rotatable Bond Count 2 Exact Mass 320.002 Da Monoisotopic Mass 320.002 Da Topological Polar Surface Area 114.000 Ų Heavy Atom Count 21 Formal Charge 0 Complexity 450.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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Reconstitution Calculator Revisões Need help choosing the grade? Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →
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