Triazavirin - ≥98% , CAS No.928659-17-0

CAS: 928659-17-0 Cat. No.: T413661 Fórmula: C₅H₇N₆NaO₅S Peso molecular: 286.2 PubChem CID: 52947239

GRADE & PURITY ≥98%

Synonyms

D81614 | UNII-G1JE34QF2S | [1,2,4]Triazolo[5,1-c][1,2,4]triazin-4(6H)-one, 7-(methylthio)-3-nitro-, sodium salt, hydrate (1:1:2) | TRIAZAVIRINE | Sodium 2-methylthio-6-nitro-1,2,4-triazol [5,1c][1,2,3]-triazin-7-one dihydrate | (1,2,4)Triazolo(5,1-C)(1,2,

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

Information

Triazavirin Triazavirin (TZV, Riamilovir) is a novel antiviral drug, a nucleoside analogue of nucleic acid that inhibits the synthesis of viral RNA and DNA and replication of genomic fragments. Triazavirin is active against influenza and a number of other viruses. Triazavirin is an effective protective agent on the transmission stage of influenza.

Specifications

Sinónimos

D81614 | UNII-G1JE34QF2S | [1,2,4]Triazolo[5,1-c][1,2,4]triazin-4(6H)-one, 7-(methylthio)-3-nitro-, sodium salt, hydrate (1:1:2) | TRIAZAVIRINE | Sodium 2-methylthio-6-nitro-1,2,4-triazol [5,1c][1,2,3]-triazin-7-one dihydrate | (1,2,4)Triazolo(5,1-C)(1,2,

Especificações e pureza

≥98%

Mecanismos bioquímicos e fisiológicos

Triazavirin (TZV, Riamilovir) is a novel antiviral drug, a nucleoside analogue of nucleic acid that inhibits the synthesis of viral RNA and DNA and replication of genomic fragments. Triazavirin is active against influenza and a number of other viruses. Tr

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Pureza

≥98%

Propriedades do produto

• ALogP: -0.184
• Ligação rotativa: 2

Nomes e identificadores

• Pubchem Sid: 528769081
• Sorrisos canónicos: CSC1=NN2C(=C(N=NC2=N1)[N+](=O)[O-])[O-].O.O.[Na+]
• IUPAC Name: sodium;7-methylsulfanyl-3-nitro-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4-olate;dihydrate
• InChIKey: GDVSBVWTWGUDAW-UHFFFAOYSA-M
• INCHI: 1S/C5H4N6O3S.Na.2H2O/c1-15-5-6-4-8-7-2(11(13)14)3(12)10(4)9-5;;;/h12H,1H3;;2*1H2/q;+1;;/p-1
• SMILES isoméricas: CSC1=NN2C(=C(N=NC2=N1)[N+](=O)[O-])[O-].O.O.[Na+]
• PubChem CID: 52947239
• Peso molecular: 286.2

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organosulfur compounds
    • Classe Thioethers
      • Subclass Aryl thioethers

• Kingdom: Organic compounds
• Superclass: Organosulfur compounds
• Classe: Thioethers
• Subclass: Aryl thioethers
• Intermediate Tree Nodes: Not available
• Direct Parent: Aryl thioethers
• Alternative Parents: Nitroaromatic compounds Alkylarylthioethers 1,2,4-triazines Imidolactams Triazoles Heteroaromatic compounds Sulfenyl compounds Propargyl-type 1,3-dipolar organic compounds Azacyclic compounds Organic oxoazanium compounds Organic oxides Organic sodium salts Hydrocarbon derivatives Organic zwitterions Organonitrogen compounds Organooxygen compounds Organopnictogen compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Aryl thioether - Nitroaromatic compound - Alkylarylthioether - Triazine - Imidolactam - 1,2,4-triazine - Azole - 1,2,4-triazole - Heteroaromatic compound - Organic nitro compound - C-nitro compound - Organic alkali metal salt - Azacycle - Organoheterocyclic compound - Organic oxoazanium - Sulfenyl compound - Allyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Hydrocarbon derivative - Organic oxygen compound - Organic zwitterion - Organic salt - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organic sodium salt - Organic oxide - Aromatic heteropolycyclic compound
• Descrição: This compound belongs to the class of organic compounds known as aryl thioethers. These are organosulfur compounds containing a thioether group that is substituted by an aryl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Alvos associados (não humanos)

Influenza B virus (2113 Activities)

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Oryctolagus cuniculus (11301 Activities)

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Influenza A virus (11224 Activities)

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MDCK (10148 Activities)

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Mecanismos de ação

Propriedades químicas e físicas

• Solubilidade: Solubility (25°C) In vitro DMSO: 57 mg/mL (199.16 mM); Water: 20 mg/mL (69.88 mM); Ethanol: Insoluble
• Sensibilidade: Moisture sensitive.
• DMSO (mg/mL) Solubilidade máxima: 57
• DMSO (mM) Solubilidade máxima: 199.16142557652
• Água (mg/mL) Solubilidade máxima: 20
• Água (mM) Solubilidade máxima: 69.8812019566737
• Peso molecular: 286.200 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 1
• Exact Mass: 286.01 Da
• Monoisotopic Mass: 286.01 Da
• Topological Polar Surface Area: 152.000 Ų
• Heavy Atom Count: 18
• Formal Charge: 0
• Complexity: 262.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 4

XLogP3