Trillin - 10mM in DMSO , CAS No.14144-06-0

CAS: 14144-06-0 Cat. No.: T580549 Fórmula: C₃₃H₅₂O₈ Peso molecular: 576.76 PubChem CID: 11827970

GRAU & PUREZA 10mM in DMSO

Synonyms

Diosgeninglucoside | Diosgenin-glucoside | (25R)-3beta-(beta-D-Glucopyranosyloxy)spirost-5-ene | AKOS015960440 | MS-30378 | (3beta,25R)-spirost-5-en-3-yl beta-D-glucopyranoside | Collettiside I | 1H-Pyrrole-2,4-dicarboxylicacid, 3,5-dimethyl- | 8KI671F2NS

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral

Product description：

Diosgenin glucoside is a saponin compound from tritulus terrestris L., which provides neuroprotection by regulating microglia M1 polarization. Diosgenin glucoside protects the spinal cord from injury by regulating autophagy and reducing apoptosis.

Especificações

Sinónimos

Diosgeninglucoside | Diosgenin-glucoside | (25R)-3beta-(beta-D-Glucopyranosyloxy)spirost-5-ene | AKOS015960440 | MS-30378 | (3beta,25R)-spirost-5-en-3-yl beta-D-glucopyranoside | Collettiside I | 1H-Pyrrole-2,4-dicarboxylicacid, 3,5-dimethyl- | 8KI671F2NS

Especificações e pureza

10mM in DMSO

Condições de armazenamento de armazenamento

Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Nomes e identificadores

Pubchem Sid

528771679

Sorrisos canónicos

CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)O)O)O)C)C)C)OC1

IUPAC Name

(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxyoxane-3,4,5-triol

InChIKey

WXMARHKAXWRNDM-GAMIEDRGSA-N

INCHI

1S/C33H52O8/c1-17-7-12-33(38-16-17)18(2)26-24(41-33)14-23-21-6-5-19-13-20(8-10-31(19,3)22(21)9-11-32(23,26)4)39-30-29(37)28(36)27(35)25(15-34)40-30/h5,17-18,20-30,34-37H,6-16H2,1-4H3/t17-,18+,20+,21-,22+,23+,24+,25-,26+,27-,28+,29-,30-,31+,32+,33-/m1/s1

SMILES isoméricas

C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5(CC[C@@H](C6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O)C)C)C)OC1

PubChem CID

11827970

Peso molecular

576.76

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Classe Steroids and steroid derivatives
      • Subclass Steroidal glycosides

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Classe: Steroids and steroid derivatives
• Subclass: Steroidal glycosides
• Intermediate Tree Nodes: Not available
• Direct Parent: Steroidal saponins
• Alternative Parents: Triterpenoids Spirostanes and derivatives Delta-5-steroids O-glycosyl compounds Ketals Oxanes Monosaccharides Tetrahydrofurans Secondary alcohols Polyols Oxacyclic compounds Primary alcohols Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteropolycyclic compounds
• Substituents: Steroidal saponin - Triterpenoid - Spirostane skeleton - Delta-5-steroid - Glycosyl compound - O-glycosyl compound - Ketal - Monosaccharide - Oxane - Tetrahydrofuran - Secondary alcohol - Polyol - Oxacycle - Acetal - Organoheterocyclic compound - Primary alcohol - Alcohol - Organooxygen compound - Hydrocarbon derivative - Organic oxygen compound - Aliphatic heteropolycyclic compound
• Descrição: This compound belongs to the class of organic compounds known as steroidal saponins. These are saponins in which the aglycone moiety is a steroid. The steroidal aglycone is usually a spirostane, furostane, spirosolane, solanidane, or curcubitacin derivative.
• External Descriptors: monosaccharide derivative - spiroketal - hexacyclic triterpenoid - sterol 3-beta-D-glucoside

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Alvos associados (humanos)

IL2 Tchem Interleukin-2 (1 Activities)

Discover Target: IL2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Alvos associados (não humanos)

Il2 Interleukin-2 (29 Activities)

Discover Target: Il2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mus musculus (284745 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de ação

Propriedades químicas e físicas

• Peso molecular: 576.800 g/mol
• XLogP3: 4.100
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 3
• Exact Mass: 576.366 Da
• Monoisotopic Mass: 576.366 Da
• Topological Polar Surface Area: 118.000 Ų
• Heavy Atom Count: 41
• Formal Charge: 0
• Complexity: 1030.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 16
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1