Tyloxapol - BioReagent , CAS No.25301-02-4

CAS: 25301-02-4 Cat. No.: T755645 Fórmula: (C₁₅H₂₁O(C₂H₄O)m)n Peso molecular: 261.38 (monomer) Número CE: 684-193-2

GRADE & PURITY BioReagent

Storage

Room temperature

Shipped In

Normal

Visão geral

Tyloxapol is a biocompatible surfactant

A nonionic liquid polymer of the alkyl aryl polyether alcohol type. Used as a surfactant.

Application:

Tyloxapol has been used in a study to assess the enhanced pulmonary absorption of recombinant human insulin. It has also been used in a study to investigate the metabolic pathways promoting intrahepatic fatty acid accumulation in methionine and choline deficiency.

Specifications

Especificações e pureza

BioReagent

Condições de armazenamento de armazenamento

Room temperature

Enviado em

Normal

Grau

BioReagent

Nomes e identificadores

• Pubchem Sid: 528771026
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/528771026
• Sorrisos canónicos: CC(C)(C)CC(C)(C)C1=CC=C(C=C1)O.C=O.C1CO1
• IUPAC Name: formaldehyde;oxirane;4-(2,4,4-trimethylpentan-2-yl)phenol
• InChIKey: MDYZKJNTKZIUSK-UHFFFAOYSA-N
• INCHI: 1S/C14H22O.C2H4O.CH2O/c1-13(2,3)10-14(4,5)11-6-8-12(15)9-7-11;1-2-3-1;1-2/h6-9,15H,10H2,1-5H3;1-2H2;1H2
• SMILES isoméricas: CC(C)(C)CC(C)(C)C1=CC=C(C=C1)O.C=O.C1CO1
• WGK Alemanha: 2
• RTECS: SM9750000
• Peso molecular: 261.38 (monomer)

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Classe Organooxygen compounds
      • Subclass Carbonyl compounds

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Classe: Organooxygen compounds
• Subclass: Carbonyl compounds
• Intermediate Tree Nodes: Not available
• Direct Parent: Carbonyl compounds
• Alternative Parents: Organic oxides Hydrocarbon derivatives
• Molecular Framework: Not available
• Substituents: Organic oxide - Hydrocarbon derivative - Carbonyl group - Aromatic heteromonocyclic compound
• Descrição: This compound belongs to the class of organic compounds known as carbonyl compounds. These are organic compounds containing a carbonyl group, with the general structure RC(=O)R', where R=organyl, R'=H, N, O, organyl group or halide group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriedades químicas e físicas

• Ponto de inflamação (°F): 235.4 °F
• Ponto de inflamação (°C): 113°C
• Peso molecular: 280.400 g/mol
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 280.204 Da
• Monoisotopic Mass: 280.204 Da
• Topological Polar Surface Area: 49.800 Ų
• Heavy Atom Count: 20
• Formal Charge: 0
• Complexity: 204.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3

Referências

1. Qiuhe Wang, Zheng Wu, Feifei Wang, Hua Zhang, Li Gan.  (2023)  Tacrolimus-Loaded Cationic Nanoemulsion In-Situ Gel System: In-Vitro Characterization and Performance in a Dry-Eye Rabbit Model.  JOURNAL OF PHARMACEUTICAL SCIENCES,      [PMID:37453530] [10.1016/j.xphs.2023.05.001]

2. Junming Li, Xinxin Liang, Shuo Ma, Jingxin Gou, Tian Yin, Haibing He, Xing Tang, Jiansong Zhao, Yu Zhang.  (2026)  Tacrolimus cationic nanoemulsion enhances ocular surface retention for the treatment of dry eye disease and allergic conjunctivitis.  EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS,      [PMID:42520946] [10.1016/j.ejpb.2026.115199]